第一篇:蒋悟生《生物专业英语》教学案
蒋悟生《生物专业英语》教/学案
Lesson One(4学时)Inside the Living Cell: Structure andFunction of Internal Cell Parts
Lesson One(4学时)
Inside the Living Cell: Structure andFunction of Internal Cell Parts
教学目的:使学生掌握细胞的组成结构(各种细胞器以及它们在细胞中的位置),以及结构与功能之间的关系。各细胞器及功能相关英语词汇以及主要用法。
教学重点:各细胞器的概念和功能,及相关英语词汇的掌握 教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:3月22日;3月29日 教学内容:
Cytoplasm: The Dynamic, Mobile Factory 细胞质:动力工厂
Most of the properties we associate with life are properties of the cytoplasm.Much of the mass of a cell consists of this semifluid substance, which is bounded on the outside by the plasma membrane.Organelles are suspended within it, supported by the filamentous network of the cytoskeleton.Dissolved in the cytoplasmic fluid are nutrients, ions, soluble proteins, and other materials needed for cell functioning.生命的大部分特征表现在细胞质的特征上。细胞质大部分由半流体物质组成,并由细胞膜(原生质膜)包被。细胞器悬浮在其中,并由丝状的细胞骨架支撑。细胞质中溶解了大量的营养物质,离子,可溶蛋白以及维持细胞生理需求的其它物质。
The Nucleus: Information Central(细胞核:信息中心)
The eukaryotic cell nucleus is the largest organelle and houses the genetic material(DNA)on chromosomes.(In prokaryotes the hereditary material is found in the nucleoid.)The nucleus also contains one or two organelles-the nucleoli-that play a role in cell division.A pore-perforated sac called the nuclear envelope separates the nucleus and its contents from the cytoplasm.Small molecules can pass through the nuclear envelope, but larger molecules such as mRNA and ribosomes must enter and exit via the pores.真核细胞的细胞核是最大的细胞器,细胞核对染色体组有保护作用(原核细胞的遗传物质存在于拟核中)。细胞核含有一或二个核仁,核仁促进细胞分裂。核膜贯穿许多小孔,小分子可以自由通过核膜,而象mRNA和核糖体等大分子必须通过核孔运输。
Organelles: Specialized Work Units(细胞器:特殊的功能单位)
All eukaryotic cells contain most of the various kinds of organelles, and each organelle performs a specialized function in the cell.Organelles described in this section include ribosomes, the endoplasmic reticulum, the Golgi complex, vacuoles, lysosomes, mitochondria, and the plastids of plant cells.所有的真核细胞都含有多种细胞器,每个细胞器都有其特定功能。本节主要介绍核糖体,内质网,高尔基体系,液泡,溶酶体,线粒体和植物细胞中的质体。The number of ribosomes within a cell may range from a few hundred to many thousands.This quantity reflects the fact that, ribosomes are the sites at which amino acids are assembled into proteins for export or for use in cell processes.A complete ribosome is composed of one larger and one smaller subunit.During protein synthesis the two subunits move along a strand of mRNA, “reading” the genetic sequence coded in it and translating that sequence into protein.Several ribosomes may become attached to a single mRNA strand;such a combination is called a polysome.Most cellular proteins are manufactured on ribosomes in the cytoplasm.Exportable proteins and membrane proteins are usually made in association with the endoplasmic reticulum.核糖体的数量变化从几百到几千,核糖体是氨基酸组装成蛋白质的重要场所。完整的核糖体由大亚基和小亚基组成。核糖体沿着mRNA移动并阅读遗传密码,翻译成蛋白质。一条mRNA上可能有多个核糖体,称多聚核糖体。大多数细胞蛋白是由细胞质中核糖体生产。输出蛋白和膜蛋白通常与内质网有关。
The endoplasmic reticulum, a lacy array of membranous sacs, tubules, and vesicles, may be either rough(RER)or smooth(SER).Both types play roles in the synthesis and transport of proteins.The RER, which is studded with polysomes, also seems to be the source of the nuclear envelope after a cell divides.内质网,带有花边的生物囊,有管状,泡状之分,以及光滑和粗糙面区别。两种都与蛋白质的合成和运输有关。粗糙内质网上分布许多核糖体,也可能提供细胞分裂后所需的细胞膜。
SER lacks polysomes;it is active in the synthesis of fats and steroids and in the oxidation of toxic substances in the cell.Both types of endoplasmic reticulum serve as compartments within the cell where specific products can be isolated and subsequently shunted to particular areas in or outside the cell.光滑内质网上无核糖体,主要作用是脂肪和类固醇的合成以及细胞内有毒物质的氧化。两种内质网合成的产物在其中进行分流或运输到细胞外。
Transport vesicles may carry exportable molecules from the endoplasmic reticulum to another membranous organelle, the Golgi complex.Within the Golgi complex molecules are modified and packaged for export out of the cell or for delivery else where in the cytoplasm.运输小泡能够将可运输分子从内质网运输到高尔基复合体上。在高尔基复合体中修饰,包装后输出细胞或传递到细胞质中的其他场所。
Vacuoles in cells appear to be hollow sacs but are actually filled with fluid and soluble molecules.The most prominent vacuoles appear in plant cells and serve as water reservoirs and storage sites for sugars and other molecules.Vacuoles in animal cells carry out phagocytosis(the intake of particulate matter)and pinocytosis(vacuolar drinking).细胞中的液泡好象是中空的,但实际上充满了液体和可溶分子。最典型的液泡存在于植物细胞中,储备水,糖以及其它分子。动物中的液泡起吞噬和胞饮作用。
A subset of vacuoles are the organelles known as lysosomes, which contain digestive enzymes(packaged in lysosomes in the Golgi complex)that can break down most biological macromolecules.They act to digest food particles and to degrade damaged cell parts.溶酶体是液泡亚单位,含有消化酶,降解大部分生物大分子。消化食物微粒和降解损伤的细胞残片。Mitochondria are the sites of energy-yielding chemical reactions in all cells.In addition, plant cells contain plastids that utilize light energy to manufacture carbohydrates in the process of photosynthesis.It is on the large surface area provided by the inner cristae of mitochondria that ATP-generating enzymes are located.Mitochondria are self-replicating, and probably they are the evolutionary descendants of what were once free-living prokaryotes.线粒体是细胞中化学产能的场所。另外,植物细胞中的质体在光合作用中利用光能产生碳水化合物,线粒体内嵴上提供了很大的表面积并分布着产ATP酶。线粒体自我复制,并且可能是自由生活的原核生物在进化中形成的后代。There are two types of plastids: leucoplasts, which lack pigments and serve as storage sites for starch, proteins, and oils;and chromoplasts, which contain pigments.The most important chromoplasts are chloroplasts-organelles that contain the chlorophyll used in photosynthesis.The internal structure of chloroplasts includes stacks of membranes called grana, which are embedded in a matrix called the stroma.质体有两种类型:白色体,缺乏色素,是淀粉,蛋白质和油的储备场所;色质体,含有色素。叶绿体是最重要的色质体,含有与光合作用有关的叶绿素。叶绿体的内部结构是由多层膜形成的叶绿体基粒,其中包埋在基质中的基粒称子座。The Cytoskeleton(细胞骨架)
All eukaryotic cells have a cytoskeleton, which is a convoluted latticework of filaments and tubules that appears to fill all available space in the cell and provides support for various other organelles.A large portion of the cytoskeleton consists of threadlike microfilaments composed mainly of the contractile protein actin.They are involved in many types of intracellular movements in plant and animal cells.A second protein, myosin, is involve in the contraction of muscle cells.Another main structural component of the cytoskeleton consists of microtubules, which are composed of the globular protein tubulin and together act as scaffolding that provides a stable cell shape.Cytoskeletal intermediate filaments appear to impart tensile strength to the cell cytoplasm.Mechanoenzymes such as myosin, dynein, and kinesin interact with the cytoskeletal filaments and tubules to generate forces that cause movements.所有的细胞都有细胞骨架,网络结构的纤丝充满了它所能触及的全部空间并且对细胞器提供支持作用。细胞骨架大部分由微丝组成,微丝主要由可收缩的肌动蛋白组成。动植物细胞的许多种类型细胞内运动与肌动蛋白有关。第二类蛋白是肌球蛋白,它与肌肉细胞的收缩有关。细胞骨架的另一个主要结构成分是微管,由球状的微管蛋白组成,象脚手架一般维持细胞的稳定形态。细胞骨架的中间丝提供了细胞质伸缩动力。机械酶,例如,肌球蛋白,动力蛋白,驱动蛋白与微丝,微管相互作用产生动力而引起细胞运动。Cellular Movements(细胞运动)
Although the cytoskeleton provides some stability to cells, its microtubules and filaments and their associated proteins enable cells to move by creeping or gliding.Such movements require a solid substrate to which the cell can adhere and can be guided by the geometry of the surface.Some cells also exhibit chemotaxis, the ability to move toward or away from the source of a diffusing chemical.尽管细胞骨架提供了细胞的某些稳定性,微丝,微管及相关蛋白能使细胞爬行或滑动。这种运动需要固体基质依托并通过表面几何形状的改变而运动。某些细胞具备趋药性,即趋向或逃离扩散开的化学源。Certain eukaryotic cells can swim freely in liquid environments, propelled by whiplike cilia or flagella.Both cilia and flagella have the same internal structure: nine doublets(pairs of microtubules)are arranged in a ring and extend the length of the cilium or flagellum, and two more microtubules run down the center of the ring.Every cilium or flagellum grows only from the cell surface where a basal body is located.Movement is based on the activities of tiny dynein side arms that extend from one of the microtubules of each doublet.某些真核细胞能在液体液体中自由运动,由纤毛或鞭毛推动。纤毛和鞭毛具有同样的内部结构:九个双微管环形排列,纵向延伸,环中心是两个或以上微管组成。纤毛或鞭毛从细胞表面的基体出生长,双微管的动力蛋白臂从一侧延伸到另一侧而引起运动。
Nutrients, proteins, and other materials within most plant cells are moved about via cytoplasmic streaming.The process occurs as myosin proteins attached to organelles push against microfilaments arrayed throughout the cell.Microfilaments and microtubules are responsible for almost all major cytoplasmic movements.During cell division, microtubules of the spindle assembled from tubutin subunits near organelles called centrioles move the chromosomes.大部分植物细胞的营养,蛋白质和其它物质由细胞质流运输。这个过程是由于依附在细胞器上的肌球蛋白反推排列在细胞周围的微丝形成的。绝大部分细胞质运动由微丝和微管完成。在细胞分裂期间,中心粒周围的由微管蛋白亚基装配形成的纺锤体微管移向染色体。课后作业:第一第二篇阅读材料
答案:1B,2C,3B,4B,5D,6c;1A,2B,3D,4A
Glossary
cytoplasm(细)胞质
The living contents of a cell bounded externally by the plasmalemma, including an aqueous ground substance(hyaloplasm, cell sap, or cell matrix)containing organelles and various inclusions but excluding the nucleus and visible vacuoles.cytoskeleton
细胞骨架
Of eukaryotic cells, an internal “skeleton”.Its microtubules and other components structurally support the cell, organize and move its inteftial components.The cytoskeleton also helps free-living cells move through their environment.nucleus
细胞核,核(复数 nuclei)The organelle of the eukaryote cell that contains
the
chromosomes and hence ultimately controls cellular activity and inheritance through the activity of the genetic material, DNA chromosome 染色体
A DNA-histone thread residing in the nucleus of a cell.Each chromosome possesses two telomeres and a centromere, and some contain a nucleolus organizer.RNA proteins are invariably associated with the chromosome.nucleoid
拟核,类核,核质体
The DNA-containing area of a prokaryote cell, analogous to the eukaryote nucleus but not membrane bounded.nucleoli
核仁(单数nucleolus)
Nuclear structures composed of completed or partially completed ribosomes and the specific parts of chromosomes that contain the infon-nation for their construction.nuclear envelope
核膜,核被膜
A double membrane(two lipid bilayers and associated proteins)that is the outermost portion of a cell nucleus.ribosome
核糖体
Small structures composed of two protein and ribonucleic acid subunits involved in the assembly of proteins from amino acids.polysome多核糖体
Of protein synthesis, several ribosomes all translating the same messenger RNA molecule,one after the other.endoplasmic reticulum
内质网
Folded membranes and tubes throughout the eukaryotic cell that provide a large surface upon which chemical activities take place.Golgi complex
高尔基复合体
A stack of flattened, smooth, membranous sacs;the site of synthesis and packaging of certain molecules in eukaryotic cells.vacuole
液泡
Storage container within the cytoplasm of a cell having a surrounding membrane.phagocytosis
吞噬作用 The process by which the cell wraps around a particle and engulfs it.pinocytosis
胞饮作用
The process by which a cell engulfs some molecules dissolved in water lysosome
溶酶体
A specialized organelle that holds a mixture of hydrolytic enzymes.mitochondrion
线粒体(复数 mitochondria)A membranous organelle resembling a small bag with a larger bag resembling a small bag with a larger bag inside that is folded back on itself;serves as the site of aerobic cellular respiration.plastid
质体
An organelle present in all plants except bacteria, blue-green algae, and fungi;it is enclosed by two membranes(the envelope)and has various functions chloroplast
叶绿体
A plastid in which photosynthesis is carried out.Chloroplasts occur in all photosynthetic organisms except photosynthetic bacteria blue-green algae.stroma基质,子座(复数stromata)
Region within a chloroplast that has no chlorophyll.microfilament
微丝,纤丝
Long, fiberlike structures made of protein and found in cells, often in close association with the microtubules;provide structural support and enable movement.actin 肌动蛋白
A globular contractile protein.In muscle cells, actin interacts with another protein, myosin, to bring about contraction.myosin ['maiesin]
肌球蛋白
A protein that, with actin, constitutes the principal element of the contractile apparatus of muscle.microtubute微管
Small, hollow tubes of protein that function throughout the cytoplasm to provide structural support and enable movement.tubulin
微管蛋白
A protein that is the major constituent of microtubules.dynein
动力蛋白,动素
A group of at least four distinct proteins found in the flagella and microtubules of eukaryotic cells and possessing ATPase activity.chemotaxis趋化性
A locomotory movement of an organism or cell in response to, and directed by, an directional stimulus.cilia
纤毛
Numerous short, hairlike structures projecting from the cell surface that enable locomotion.flagella
鞭毛(单数flagellum)
Long, hairlike structures projecting from the cell surface that enable locomotion.basal body 基体
A body identical in structure to a centriole, found always at the base of a cilium or eukaryote flagellum.centriole 中心粒
An organelle located close to the nucleus in most animal and lower plant cells but absent from prokaryotes and higher plants.Lesson Two(2学时)
Photosynthesis
教学目的:使学生掌握细胞的光合作用机理,光合系统Ⅰ与光合系统Ⅱ结构与功能之间的关系。相关英语词汇以及主要用法。
教学重点:光合作用中相关的概念和功能,及相关英语词汇的掌握 教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:4月5日 教学内容:
Photosynthesis occurs only in the chlorophyll-containing cells of green plants, algae, and certain protists and bacteria.Overall, it is a process that converts light energy into chemical energy that is stored in the molecular bonds.From the point of view of chemistry and energetics, it is the opposite of cellular respiration.Whereas cellular respiration is highly exergonic and releases energy, photosynthesis requires energy and is highly endergonic.光合作用只发生在含有叶绿素的绿色植物细胞,海藻,某些原生动物和细菌之中。总体来说,这是一个将光能转化成化学能,并将能量贮存在分子键中,从化学和动能学角度来看,它是细胞呼吸作用的对立面。细胞呼吸作用是高度放能的,光合作用是需要能量并高吸能的过程。
Photosynthesis starts with CO2 and H2O as raw materials and proceeds through two sets of partial reactions.In the first set, called the light-dependent reactions, water molecules are split(oxidized), 02 is released, and ATP and NADPH are formed.These reactions must take place in the presence of light energy.In the second set, called light-independent reactions, CO2 is reduced(via the addition of H atoms)to carbohydrate.These chemical events rely on the electron carrier NADPH and ATP generated by the first set of reactions.光合作用以二氧化碳和水为原材料并经历两步化学反应。第一步,称光反应,水分子分解,氧分子释放,ATP和NADPH形成。此反应需要光能的存在。第二步,称暗反应,二氧化碳被还原成碳水化合物,这步反应依赖电子载体NADPH以及第一步反应产生的ATP。
Both sets of reactions take place in chloroplasts.Most of the enzymes and pigments for the lightdependent reactions are embedded in the thylakoid membrane of chloroplasts.The dark reactions take place in the stroma.两步反应都发生在叶绿体中。光反应需要的大部分酶和色素包埋在叶绿体的类囊体膜上。暗反应发生在基质中。
How Light Energy Reaches Photosynthetic Cells(光合细胞如何吸收光能的)
The energy in light photons in the visible part of the spectrum can be captured by biological molecules to do constructive work.The pigment chlorophyll in plant cells absorbs photons within a particular absorption spectrums statement of the amount of light absorbed by chlorophyll at different wavelengths.When light is absorbed it alters the arrangement of electrons in the absorbing molecule.The added energy of the photon boosts the energy condition of the molecule from a stable state to a less-stable excited state.During the light-dependent reactions of photosynthesis, as the absorbing molecule returns to the ground state, the “excess” excitation energy is transmitted to other molecules and stored as chemical energy.生物分子能捕获可见光谱中的光能。植物细胞中叶绿素在不同光波下吸收部分吸收光谱。在吸收分子中,光的作用使分子中的电子发生重排。光子的能量激活了分子的能量状态,使其从稳定态进入不稳定的激活态。All photosynthetic organisms contain various classes of chlorophylls and one or more carotenoid(accessory)pigments that also contribute to photosynthesis.Groups of pigment molecules called antenna complexes are present on thylakoids.Light striking any one of the pigment molecules is funneled to a special chlorophyll a molecule, termed a reaction-center chlorophyll, which directly participates in photosynthesis.Most photosynthetic organisms possess two types of reaction-center chlorophylls, P680 and P700, each associated with an electron acceptor molecule and an electron donor.These aggregations are known respectively as photosystem Ⅰ(P700)and photosystem Ⅱ(P680).所有的光合作用生物含有不同等级的叶绿素和一个或多个类胡萝卜素(光合作用的辅助色素)。称作天线复合体的色素分子群存在于类囊体中。激活色素分子的光能进入叶绿素反应中心,其直接参与光合作用。大部分光反应细胞器拥有两套反应中心,P680和P700,每个光系统都含有一个电子受体和电子供体。这些集合体就是大家熟识的光合系统Ⅰ和光合系统Ⅱ。
The Light-Dependent Reaction: Converting Solar Energy into Chemical-Bond Energy 光反应:光能转化成化学键能
The photosystems of the light-dependent reactions are responsible for the packaging of light energy in the chemical compounds ATP and NADPH.This packaging takes place through a series of oxidation reduction reactions set in motion when light strikes the P680 reaction center in photosystem Ⅱ.In this initial event water molecules are cleaved, oxygen is released, and electrons are donated.These electrons are accepted first by plastoquinone and then by a series of carriers as they descend an electron transport chain.For each four electrons that pass down the chain, two ATPs are formed.The last acceptor in the chain is the P700 reaction center of photosystem Ⅰ.At this point incoming photons boost the energy of the electrons, and they are accepted by ferredoxin.Ferredoxin is then reoxidized, and the coenzyme NADP+ is reduced to the NADPH.The ATP generated previously and the NADPH then take part in the light independent reactions.光反应的光系统将光能转化成化学复合物ATP和NADPH。当光激活光系统Ⅱ的光反应中心时,通过一系列的氧化还原反应实现能量的传递。反应开始时,水被分解,氧被释放并提供电子。电子首先传递给质体醌,然后通过一系列载体形成的电子传递链。每传递4个电子,形成2个ATP。最后一个受体存在于光反应系统Ⅰ的反应中心里。此处光子激活电子,电子传递给铁氧还蛋白。铁氧还蛋白再氧化,并且辅酶NADP+还原成NADPH。早期产生的ATP和NADPH进入暗反应。
The production of ATP from the transport of electrons excited by light energy down an electron transport chain is termed photophosphorylation.The one-way flow of electrons through photosystems II and I is called noncyclic photophosphorylation;plants also derive additional ATP through cyclic photophosphorylation, in which some electrons are shunted back through the electron transport chain between photosystems Ⅱ and Ⅰ.由电子传递链偶连产生ATP的过程称为光合磷酸化。通过光合系统Ⅱ流经光合系统Ⅰ的电子路径称非循环式光合磷酸化;植物通过循环式光合磷酸化获得额外的ATP,一些电子在光合系统Ⅰ和Ⅱ之间的电子传递链中回流。
The Light-Independent Reactions: Building Carbohydrates 暗反应:碳水化合物的形成
In the light-independent reactions of photosynthesis, which are driven by ATP and NADPH, C02 is converted to carbohydrate.The reactions are also known as the Calvin-Benson cycle.Atmospheric CO2, is fixed as it reacts with ribulosebiphosphate(RuBP), a reaction that is catalyzed by the enzyme ribulosebiphosphate carboxylase.The reduction Of C02 to carbohydrate(fructose diphosphate)is completed via several more steps of the cycle.Finally, RUBP is regenerated so that the cycle may continue.由ATP和NADPH驱动的暗反应中,二氧化碳转化成碳水化合物。即卡尔文循环。二磷酸核酮糖固定二氧化碳,由二磷酸核酮糖羧化酶催化。
Oxygen: An Inhibitor of photosynthesis(氧:光合作用的抑制因子)High levels of oxygen in plant cells can disrupt photosynthesis and can also cause photorespiration-an inefficient fun of the dark reactions in which 02 is fixed rather than C02 and no carbohydrate is produced.Reprieve from Photorespiration: The C4 Pathway Most plants are C3 plants;they experience decreased carbohydrate production under hot, dry conditions as a result of the effects of photorespiration.Among C4 plants, however, special leaf anatomy and a unique biochemical pathway enable the plant to thrive in and conditions.Thus C4 plants lessen photorespiration by carrying out photosynthesis only in cells that are insulated from high levels of CO2.They also possess a novel mechanism for carbon fixation.大部分植物是碳3植物,在高温干旱条件下,由于光呼吸作用而使碳水化合物的合成降低。而在大多数的碳4植物中,由于叶脉的特殊构造和独特的化学路径使植物依然很茂盛。这是碳固定的一个新机制。
课后作业:第一篇阅读材料 答案:1B,2A,3A,4D,5C,6c Glossary
light-dependent reactions 光反应-The first stage in photosynthesis, driven by light energy.Electrons that trap the sun's energy pass the energy to high-energy carriers such as ATP or NADPH, where it is stored in chemical bonds.light-independent reactions 暗反应
The second stage of photosynthesis, also called the Calvin-Benson cycle, which does not require light.During the six steps of the cycle, carbon is fixed and carbohydrates are formed.chloroplast 叶绿体
A plastid in which photosynthesis is carried out.Chloroplasts occur in all photosynthetic organisms except photosynthetic bacteria and blue-green algae.absorption spectrum 吸收光谱,吸收谱
The spectrum obtained when radiation(light, ultraviolet radiation, etc.)from a source giving a continuous spectrum is passed through a substance.Calvin-Benson cycle 卡尔文?本森循环
Cyclic reactions that are the “synthesis” part of the light-independent reactions of photosynthesis.In land plants, RUBP, or some other compound to which carbon has
been affixed, under goes rearrangements that lead to formation of a sugar phosphate and to regeneration of the RUBP.The cycle runs on ATP and NADPH from light-dependent reactions.carotenoid 类胡萝卜素
Light-sensitive, accessory pigments that transfer absorbed energy to chlorophylls.They absorb violet and blue wave-lengths but transmit red, orange, and yellow.chlorophyll 叶绿素
The green substance of plants by which photosynthesis is accomplished;it is usually localized in intracellular organelles called chloroplasts.cyclic photophosphorylation 环形光合磷酸化(作用)
Cyclic photophosphorylation is coupled to cyclicelectron flow, in which ATP is the only product.C3 plant 三碳植物 A plant in which the light-independent reactions of photosynthesis start with a threecarbon compound.Most plants are C3 plants.C4 plant 四碳植物
A plant such as corn in which the light independent reactions of photosynthesis star with a four-carbon compound.noncyclic photophosphorylation
非环形光合磷酸化作用
Noncyclic photophosphorylation is coupled to noncyclic electron flow, the electrons being used to reduce NADP+ as well as to make ATP.photon 光子
A particle that has zero mass or charge and unit spin, the quantum of the electromagnetic field and carrier of the electromagnetic force.photophosphorylation 光合磷酸化作用
The synthesis of ATP from phosphate and ADP during photosynthesis, using light energy.photorespiration 光呼吸
A light-dependent type of respiration that occurs in most photosynthetic plants and differs from normal(or dark)respiration.photosynthesis 光合作用
The synthesis of organic compounds by reduction of carbon dioxide using light energy absorbed by chorophyll.photosystem 光合系统
One of the clusters of light-trapping pigments embedded in photosynthetic membranes.Photosystem I operates during the cyclic pathway;photosystem Ⅱ operates during both the cyclic and noncyclic pathways.ribulosebiphosphate(RUBP)核酮糖二磷酸
A compound with a backbone of five carbon atoms that is required for carbon fixation in the Calvin-Benson cycle of photosynthesis.thylakoid 类囊体
One of a number of flattened fluid-filled sacs that form the photosynthetic lamellar system of chloroplasts, photosynthetic bacteria, and blue-green algae.Lesson Three(2学时)
Cellular Reproduction: Mitosis and Meiosis
教学目的:使学生掌握细胞的有丝分裂和无丝分裂的作用机理,有丝分裂和无丝分裂之间的区别和相同点。相关英语词汇以及主要用法。
教学重点:有丝分裂和无丝分裂中相关的概念和功能,及相关英语词汇的掌握 教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:4月12日 教学内容:
The Nucleus and Chromosomes The cell nucleus is the main repository of genetic information.Within the nucleus are the chromosomes tightly coiled strands of DNA and clusters of associated proteins.Long stretches of the continuous DNA molecule wind around these clusters of proteins, or histones, forming beadlike complexes known as nucleosomes.More coiling and supercoiling produces a dense chromosome structure.Each long strand of DNA combines with histones and nonhistone proteins to make up the substance chromatin.细胞核是贮藏遗传信息的主要场所。DNA盘绕成螺旋线以及相关的成簇蛋白质。DNA螺旋线缠绕成簇的组蛋白形成珠链状的核小体。这些螺旋和超螺旋形成致密的染色体组结构。每个长链DNA与组蛋白和非组蛋白一起构成染色质物质。
A pictorial display of an organism's chromosomes in the coiled, condensed state is known as a karyotype.Karyotype reveal that in most cells all but sex chromosomes are present as two copies, referred to as homologous pairs.Non-sex chromosomes are called autosomes.Organisms whose cells contain two sets of parental chromosomes are called diploid;those with cells containing a single set of parental chromosomes are called haploid.染色体致密的超螺旋状态我们称染色体组。除了性染色体外,大多数细胞的染色体组成对出现,称同源染色体对。非性染色体称常染色体。生物细胞含有两套父母本染色体的称二倍体;含有单套染色体的称单倍体。
The Cell Cycle The cell cycle is a regular sequence in which the cell grows, prepares for division, and divides to form two daughter cells, each of which then repeats the cycle.Such cycling in effect makes single-celled organisms immortal.Many cells in multicellular organisms, including animal muscle and nerve cells, either slow the cycle or break out of it altogether.在细胞生长过程中,细胞循环遵循特定程序,分裂准备,分裂成2个子细胞,子细胞再循环。此循环使得单细胞永生。多细胞生物中的许多细胞,包括动物肌肉和神经细胞,要么降低循环速度,要么同时分裂。The normal cell cycle consists of four phases.The first three include G1, the period of normal metabolism;S phase, during which normal synthesis of biological molecules continues, DNA is replicated, and histones are synthesized;and G2, a brief period of metabolism and additional growth.Together the G1, S, and G2 phases are called interphase.The fourth phase of the cell cycle is M phase, the period of mitosis, during which the replicated chromosomes condense and move and the cell divides.It is believed that properties of the cell cytoplasm control the cell cycle, along with external stimulators and inhibitors such as chalones.正常细胞循环由4个时期组成。头三期包括G1,正常新陈代谢;S期,正常新陈代谢同时,DNA复制,组蛋白合成; G2 期,短期的新陈代谢和少许生长。G1, S, 和G2称分裂间期。最后是M期,有丝分裂期,复制的染色体组浓缩,移动并细胞分裂。据称是染色质控制了细胞循环,伴随外部激活因子和抑制因子如抑素。
Mitosis: Partitioning the Hereditary Material Biologists divide the mitotic cycle into four phases.At the beginning of prophase the chromosomes each consist of two highly condensed chromatids attached to each other at a centromere.As prophase ends and metaphase begins, the condensed chromosomes become associated with the spindle.Eventually the chromosomes become arranged in a plane(called the metaphase plate)at a right angle to the spindle fibers.Next, during anaphase, the two sister chromatids of each chromosome split, and one from each pair is drawn toward each pole of the cell.During telophase nuclear envelopes begin to form around each set of chromosomes, and division of the cytoplasm takes place.生物学家将有丝分裂划分为4个阶段。分裂前期,高度浓缩的两个染色单体通过着丝粒连接在一起。在分裂前期后期和分裂中期前期,浓缩的染色体与纺锤体相连,最后以正确的角度排列在赤道板上。在分裂后期,两个姊妹单体分离,分别拽向细胞两极。在分裂末期,在每套染色体周围形成核膜,细胞质发生分裂。As mitosis proceeds, the spindle microtubules play a crucial role in ensuring that both paired and separated chromatids move in the right directions at the proper times.Each half of the spindle forms as microtubules extend from each pole of a dividing cell to the region of the metaphase plate.During prophase, other microtubules, the centromeric fibers, extend outward from the spindle poles to structures on the chromosomes called kinetochores.During anaphase the fibers begin to shorten, and the chromatids begin to move apart.在有丝分裂过程中,是纺锤体微管确保了染色单体在适当时间以正确方向进行分离。纺锤体微管由两极向赤道板延伸。在分裂前期,其它微管,着丝粒纤维延伸到染色体的动粒。在分裂后期,纤维开始变短,染色单体分离。
The spindle forms differently in plant and animal cells.In animals it is associated with centriole, while in plant and fungal cells spindle formation is associated with reions called microtubule organizing centers.植物和动物细胞形成的纺锤体不同。动物细胞与中心粒相连,而在植物和真菌细胞中,纺锤体与微管组织中心的离子相连。
Cytokinesis: Partitioning the Cytoplasm 胞质分裂:细胞质分离
The division of the cell cytoplasm at the end of mitosis is called cytokinesis.In animal cells it takes place as a ring of actin filaments contracts around the cell equator, pinching the cell in two.In plant cells, which are bounded by a cell wall, cytokinesis involves the building of a new cell plate across the dividing cell at its equator.Cell wall material is then deposited in the region of the cell plate.在动物细胞中,环形肌动蛋白丝延赤道板收缩而使细胞一分为二。在植物细胞中,在赤道板形成新的细胞板。
Meiosis: The Basis of Sexual Reproduction Meiosis is a special form of cell division that takes place in the reproductive organs that produce sex cells.Like mitosis, it takes place after DNA replication has occurred and involves two sequential nuclear divisions(meiosis I and meiosis Ⅱ).These divisions result in four daughter cells, each with half the number of chromosomes of the parent cell.The phenomenon of crossing over during meiosis results in exchanges of genetic information between chromosomes.Hence, the homologous chromosomes distributed to different progeny cells are not identical.减数分裂是性细胞分裂的特殊形式。如有丝分裂,它也是发生在DNA复制后并有连续的两个核分裂。产生4个子细胞,分别含有亲本一半的染色体数。
As in mitosis two chromatids exist for each chromosome at the beginning of prophase 1.During this phase the homologous chromosomes undergo synapsis, or pairing, which is brought about by a bridging structure of proteins and RNA called the synaptonemal complex.The homologous pairs stay together when they align on the metaphase plate.Unlike the anaphase of mitosis, however, during anaphase I the two chromatids of each chromosome stay joined at the centromere and move together to one of the two poles of the cell.It is this event that results in the halving of the chromosome number in the four daughter cells that result from meiosis.正如在有丝分裂中一样,两个同源染色单体通过蛋白质和RNA桥配对形成联会复合体。与有丝分裂不同的是,每组染色体的两个染色单体连接在着丝点上并一起移向细胞两极的一级。由此而导致4个子细胞染色体数减半。
During telophase I nuclear envelopes enclose the chromosomes in nuclei, and in most species cytokinesis(the first nuclear division)follows.The second nuclear division begins with metaphase Ⅱ, in which the chromosomes in each daughter cell again align on a metaphase plate.The centromeres finally divide, and each sister chromatid moves to one of the poles of the spindle.The next phase is telophase , followed again by cytokinesis.The result of the entire process is four haploid cells in which parental chromosomes are randomly distributed.第二次核分裂开始于分裂中期,子细胞中染色体重新排列在赤道板上。着丝粒最终分离,每个姊妹染色单体分向两极。接着胞质分裂。产生4个单倍体,父母染色体随机分配。Asexual Versus Sexual Reproduction Mitosis and meiosis, respectively, make simple cell division and sexual reproduction possible.Each means of passing on hereditary information has advantages.In asexual reproduction the parent organism gives rise to offspring that are genetic clones of the parent.The advantages of this type of reproduction are that it preserves the parent's successful genetic complement, requires little or no specialization of reproductive organs, and is more rapid than sexual reproduction.A major disadvantage of the asexual mode is that a single catastrophic event or disease may destroy an entire population of genetically identical organisms.A prime benefit of sexual reproduction is that it provides genetic variability and a ready mechanism for the elimination of deleterious mutations.It also allows “new” gene forms to arise and spread through populations.有丝分裂和减数分裂在传递遗传信息过程中各有优势。体细胞的繁殖就是父母本的克隆,其优势是保留了父母本的成功遗传信息,不需要特殊器官,比性复制快的多。但一个简单灾难性事件或疾病都可能摧毁一个细胞群体。性复制的优势是它提供了遗传可变性和现存排除有害突变的机制。也可以产生新的基因并在种群中蔓延。
课后作业:第一篇阅读材料 答案:1C,2B,3D,4B,5A,6D
Glossary
mitosis 有丝分裂
Process that results in equal and identical distribution of replicated chromosomes into two newly formed nuclei.meiosis 减数分裂
The process by which a nucleus divides into four daughter nuclei, each containing half the number of chromosomes of the parent nucleus.histone 组蛋白
One of a group of simple proteins that have a high content of the basic amino acids arginine or lysine and are found associated with nucleic acids in the chromatin of eukaryotic cells.nucleosome 核小体
The basic unit of chromatin structure in eukaryotic cells.A nucleosome consists of eight histone molecules of four different types, together with about 140 base pairs of DNA coiled around it.chromatin 染色质
The material of which the chromosomes are composed.DNA and protein are the main constituents of chromatin, most of the protein being histone.karyotype 核型,染色体组型 , The appearance of the chromosome complement of an organism or cell.homologous pair 同源染色体对
Chromosomes that pair during meiosis.Each homologue is a duplicate of one of the chromosomes contributed at syngamy by the mother or father.Homologous chromosomes contain the same linear sequence of genes and as a consequence each gene is present in duplicate.diploid二倍体
Any nucleus, cell, or organism that possesses twice the haploid number of chromosomes.haploid 单倍体 Any nucleus, cell, or organism that possesses a single set of unpaired chromosomes, interphase(cycle)分裂间期(周期)
In a cell preparing to duplicate, the interphase stage can divided into a period of initial growth(G1), a period of DNA synthesis(S), and a second growth period(G2).chalone抑素
Substances found in mammalian tissue homogenates that, when applied to intact tissue cells, inhibit mitosis, particularly in the presence of adrenaline and corticosteroids.prophase(分裂)前期
First stage of mitosis, during which individual chromosomes become visible.chromatid 染色单体
A replicated chromosome physically attached to an identical chromatid at the centromere.centromere 着丝粒
The small area of a chromosome that does not stain with basic dyes during mitosis and meiosis;at interphase it is single while the rest of the chromosome is made up of two chromatids.metaphase(分裂)中期
Second stage in mitosis, during which the chromosomes align at the equatorial plane.spindle 纺锤体
An array of microtubutes extending from pole to pole and used in the movement of chromosomes.metaphase plate 赤道板,中期板
The grouping of the chromosomes in a plane at the equator of the spindle during the metaphase stage of mitosis.anaphase 分裂后期
The third stage of mitosis, during which the centromeres split and the chromosomes move to the poles.telophase(分裂)末期
Last stage in mitosis during which daughter nuclei are formed.cytokinesis 胞质分裂
Division of the cytoplasm of one cell into two new cells.cell plate 细胞板
A plant cell structure that begins to form in the center of the cell and proceeds to the cell membrane, resulting in cytokinesis.Lesson Four(2学时)
Foundations of Genetics
教学目的:使学生了解遗传学的发展历程,掌握孟德尔遗传学的建立及经典实验。相关英语词汇以及主要用法。教学重点:孟德尔遗传学的两个定律,及相关英语词汇的掌握 教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:4月19日 教学内容:
Early Theories of inheritanee Early ideas of inheritance included Hippocrates' theory of pangenesis and August Weismands germ plasm theory.Based on experiments with mice, Weismann proposed that hereditary information in gametes transmitted traits to progeny.Both of these early views incorporated the blending theory: they held that heritable traits of the two parents blend, so that the distinct characteristics of each are lost in offspring.遗传学的早期理论包括泛生说和种质理论。基于小鼠实验,维丝曼提出遗传信息储存在配子中并将遗传信息传递给后代。这两个早期观点合起来形成融合理论:子代拥有父母本混合的遗传特征,而不完全象亲代。Gregor Mendel and the Birth of Genetics Gregor Mendel, an Augustinian monk in the monastery at Brunn, Austria, is known as the “father of genetics.” Having been exposed to theories of the particulate nature of matter while a university student and having a background in mathematics, Mendel carried out a series of carefully planned experiments that demonstrated the particulate nature of heredity.His revolutionary ideas were neither understood nor accepted until many years after Mendel died.孟德尔,众所周知的遗传学之父,是一名修道士。当他还是大学生时就提出了物质的粒子属性。孟德尔进行了一系列周密安排的实验来证实遗传的颗粒性。直到他去世后,他的理论才被理解和接受。Mendel's Classic Experiments Mendel studied genetics through plant-breeding experiments with the garden pea, a plant species that is self-fertilizing and h offspring is identical to the parent in the trait of interest).To test the blending theory, he focused his research on seven distinct characters.Each of these characters, such as seed color and plant height, present only two, clear-cut possibilities.He also recorded the type and number of all progeny produced from each pair of parent pea plants, and followed the results of each cross for two generations.孟德尔通过豌豆实验研究遗传学,豌豆是自花授粉植物和纯品系。为验证融合理论,他的研究主要集中在7个特征上。例如,种子颜色,植株高度,这些特征只有两个明确的可能性。他记录了产生的每一个子代类型和数量,在杂交产生子2代。
For each of the characters he studied, Mendel found that one trait was dominant while the other was recessive.In the second filial(F2)generation, the ratio of dominant to recessive was 3:1.Mendel deduced that this result was possible only if each individual possesses only two hereditary units, one from each parent.The units Mendel hypothesized are today known as alleles, alternative forms of genes.Genes are the basic units of heredity.An organism that inherits identical alleles for a trait from each parent is said to be homozygous for that trait;if different alleles for a trait are inherited, the organism is heterozygous for that trait.When an organism is heterozygous for a trait, the resulting phenotype for that trait expresses only the dominant allele.Thus, the organism’s phenotype—its physical appearance and properties-differs from its genotype, which may include both a dominant and a recessive allele.A pictorial representation of all possible combinations of a genetic cross is known as a Punnett square.对于每个特征而言,要么显形,要么隐性。在子2代中显形与隐性比为3∶1。只有在每个个体仅拥有两个研究遗传单元,并每个单元来自一个亲代时,实验结果才成立。此遗传单元就是今天共识的等位基因。两个一样的等位基因决定一个特征,称纯合。相反,称杂合。当生物是杂合时,它的表型由显性基因决定。因此,生物的表型与基因型是不同的。旁纳特方格可以陈列所有可能的遗传组合。The results of Mendel's experiments on dominant and recessive inheritance let to Mendel's first law: the law of segregation.This law states that for a given trait an organism inherits one allele from each parent.Together these alleles form the allele pair.When gametes are formed during meiosis, the two alleles become separated(halving of chromosome number).To gain evidence for his theory Mendel performed test crosses, mating plants of unknown genotype to plants that were homozygous recessive for the trait of interest.The ratio of dominant phenotypes(if any)in the progeny makes clear whether the unknown genotype is heterozygous, homozygous dominant, or homozygous recessive.分离定律,生物只遗传父母本等位基因对的一个等位基因。减数分裂期形成配子时两个等位基因分离。为验证此理论,他做了测交实验,即基因型未知的植物与纯合的隐性基因植物杂交。子代显性表型可以明确测得杂合基因或纯合基因的基因型。
Mendel's Ideas and the Law of independent Assortment Mendel also performed dihybrid crosses, which enabled him to consider how two traits are inherited relative to one another.This work let to the law of independent assortment, which states that the alleles of genes governing different characters are inherited independently.An apparent exception to Mendel's laws is incomplete dominance, a phenomenon in which offspring of a cross exhibit a phenotype that is intermediate between those of the parents.However, incomplete dominance reflects the fact that both alleles for the trait in question exert an effect on the phenotype.The alleles themselves remain separate.双因子杂合试验,两个特征是如何相互影响遗传的。试验结果产生独自分配定律,即等位基因独立遗传。特例是,不完全显性。子代的表型是父母本的中间类型。不完全显性说明了两个等位基因对表型都有影响。,等位基因会继续分离。
Mendel presented his ideas in 1866 in a scientific paper published by the Brunn Society for Natural History.Unfortunately, the meaning of his research was not understood by other scientists of the day.His work was rediscovered in 1900 by Carl Correns and Hugo de Vries.1866年,孟德尔在自然史上发表了他的科学论文,陈诉了他的观点。不幸的是,他的研究不被当时科学家接受。在1900年,他的著作再被发现利用。Chromosomes and Mendelian Genetics Soon after Mendel's work was rediscovered, Walter Sutton and Theodor Boveri independently proposed that the hereditary units might be located on chromosomes.Experiments to prove this hypothesis were carried out by Thomas Hunt Morgan and his students at Columbia University, in research on the sex chromosomes of fruit flies.Morgan's studies were also the first exploration of sex-linked traits.It also led to the discovery in 1916 by Calvin Bridges of the phenomenon of nondisjunction, in which a chromosome pair fails to segregate during meiosis.孟德尔著作被再发现不久,Walter Sutton 和Theodor Boveri提出,遗传单位可能定位在染色体组上。伴性遗传又导致了不分离现象的发现,即在减数分裂中,染色体对不分离。课后作业:第一篇阅读材料 答案:1C,2C,3A,4A,5B,6B Glossary
pangenesis 泛生论,泛生说
The theory of heredity postulating that germs, humours, or essences migrate from individual body cells to the sex organs and contribute to the gametes.germ plasm theory 种质学说
A substance thought to be transmitted in the gametes(germ cells)in an unchanged form from generation to generation.The germ plasm was believed to be unaffected by the environment and to give rise to the body cells.dominant 显性
The member of a pair of alleles that shows its effect in the phenotype whatever other allele is present.recessive 隐形的
The member of a pair of alleles that does not show its effect in the presence of any other allelic partner.allele 等位基因
Alternative forms of a gene for a particular characteristic(e.g., attached earlobe genes and free earlobe genes are alternative alleles for ear shape).gene 基因
A unit of heredity located on a chromosome and composed a sequence of DNA nucleotides.homozygous 纯合的
A diploid organism that has two identical alleles for particular characteristic.heterozygous 杂合的
A diploid organism that has two different alletic forms of a particular gene.Genotype 基因型 The catalog of genes of an organism, whether or not these genes are expressed.phenotype 表型
The physical, chemical, and psychological expression of genes possessed by an organism.Punnett square 旁纳特方格
A method used to determine the probabilities of combination in a zygote.law of segregation 分裂定律
When gametes are formed by a diploid organism, the alleles that control a trait separate from one another into different gametes, retaining their individuality.test cross 测交
A cross between a heterozygote of unknown genotype and an individual homozygous for the recessive genes in question.dihybrid cross 双因子杂种,双因子杂合子
A cross between individuals that differ with respect to two specified gene pairs.law of independent assortment 独立分配定律,自由组合定律
Members of one gene pair will separate from each other independently of the members of other gene pairs.incomplete dominance 不完全显性
The condition in which two allelic genes have a different effect when they are together as a heterozygote in a diploid cell than either of them have in the homozygous state nondisjunction 不分离
The failure of separation of paired chromosomes at metaphase, resulting in one daughter receiving both and the other daughter cell none of the chromosomes in question.Nondisjunction can occur during a meiotic or mitotic division.Lesson Five(2学时)
Discovering the Chemical Nature of the Gene
教学目的:使学生了解遗传学化学本质的发现过程,及相关假说,使学生掌握相关专业词汇以及主要用法。教学重点:DNA分子组成及相关英语词汇的掌握。教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:4月26日 教学内容:
Genes Code for Particular Proteins The first scientist to investigate the question of how genes affect phenotype was Sir Archibald Garrod, whose studies of alkaptonuria implied a relationship between genes and enzymes.Thirty years later Beadle and Ephrussi showed a relationship between particular genes and biosynthetic reactions responsible for eye color in fruit flies.Next, in a series of classic experiments on the effects of mutations in the bread mold Neurosporacrassa, Beadle and Tatum explored the one-gene-one-enzyme hypothesis-the idea that each gene codes for a particular enzyme.Their work paved the way for other researchers to elucidate the precise ways in which enzymes affect complex metabolic pathways.In 1949, in research on the role of hemoglobin in sickle cell anemia, Linus Pauling helped refine the one-gene-one-enzyme hypothesis into the one-gene-one-polypeptide hypothesis.Archibald Garrod是第一个研究基因是如何影响表型的科学家,他对尿黑酸症的研究揭示了基因与酶之间的关系。Beadle 和Ephrussi在三十年后对果蝇眼睛颜色的研究发现特殊基因与相关反应的生物合成有关。接着对面包发霉粗糙脉孢菌的突变试验得出一个基因一个酶的假说。他们的工作为其他工作者铺平了道路,即精确地阐明了酶影响了复杂的新陈代谢途径。在1949年,对镰刀状细胞贫血症的研究对一个基因一个酶的假说进一步上升为一个基因一个多肽。
The Search for the Chemistry and Molecular Structure of nucleic Acids Nuclei acid, originally isolated by Johann Miescher in 1871, was identified as a prime constituent of chromosomes through the use of the red-staining method developed by Feulgen in the early 1900s.Frederick Griffith's experiments with the R and S stains of pneumococci showed that an as yet unknown material from one set of bacterial could alter the physical traits of a second set.In the 1940s the team of Avery, MacLeod, and McCarty showed that this unknown material was DNA.At about the same time P.A.Levene discovered that DNA contained four nitrogenous bases, each of which was attached to a sugar molecule and a phosphate group-a combination Levene termed a nucleotide.在1871年,核酸最初是由Johann Miescher分离成功,并由Feulgen在1900年证实核酸是染色体组最基本的组成。Frederick Griffith对粗糙和光滑的肺炎球菌实验表明,不确定的某种物质可以从一组细菌转移到另一种细菌中。在1940年,确认该物质为DNA。四个碱基和磷酸分子分别连接在糖分子上,称核苷酸。Disagreement over whether DNA could carry complex genetic information was ended in the early 1950s by Martha Chase and Alfred Hershey, whose work with E.coli showed clearly that DNA, and not protein, is the bearer of genetic information.直到1950年,通过对大肠杆菌实验发现,遗传物质是DNA,而不是蛋白质。
Each DNA nucleotide contains a five-carbon sugar, deoxyribose, attached to one of four bases: adenine, guanine, cytosine, or thymine.Adenine and guanine molecules are double-ring structures called purines, while cytosine and thymine are single-ring structures called pyrimidines.The molecule made up of a base plus a sugar is termed a nucleoside.In each molecule of DNA a phosphate group links the five-carbon sugar of one nucleoside to the five-carbon sugar of the next nucleoside in the chain.This phosphate bonding creates a sugar-phosphate backbone.每个核苷酸都含有一个五碳脱氧核糖,分别连接4个碱基,即:腺嘌呤,鸟嘌呤,胞嘧啶,胸腺嘧啶。碱基连接糖称核苷。磷酸键形成磷酸骨架。
Chargaff’s rules describe the fact that(1)the amount of adenine is equal to the amount of thymine in DNA, with amount of cytosine equal to that of guanine, and(2)the ratios of A to T and of C to G vary with different species.(1)腺嘌呤与胸腺嘧啶,胞嘧啶与鸟嘌呤相等;(2)腺嘌呤与胸腺嘧啶,胞嘧啶与鸟嘌呤的比例随物种不同而不同。
The Research Race for the Molecular Structure of DNA In the late 1940s and early 1950s, researchers looking for the structure of DNA drew upon Chargaff s insight, Levene's ideas on DNA components, and two other lines of evidence.One was the suggestion of Linus Pauling that DNA might have a helical structure held in place by hydrogen bonds, and the other was X-ray diffraction photos of DNA, showing a helical structure with distance between the coils, taken by Franklin and Wilkins.直到40年代末50年代初,研究者在寻求DNA结构过程中,确立了Chargaff 的观点和, Levene的组成理论以及其他两个线索。一个是Linus Pauling的假设,DNA可能具有螺旋结构,通过氢键连接。另一个是X-衍射图片,Franklin and Wilkins提供。
Based on this information Watson and Crick proposed the double helix model of DNA-A twisted ladder-like molecule with two outer sugar phosphate chains and rungs formed by nucleotide pairs.Paired nucleotides, which always occur as A-T or G-C, are linked by hydrogen bonds.Watson and Crick also proposed that genetic information is encoded by the sequence of base pairs along the DNA molecule.基于这些信息,Watson 和 Crick提出了双螺旋结构模型,成对的核苷酸通过氢键相连,遗传信息就贮藏在碱基对中。
How DNA Replicates In their model of DNA structure and function, Watson and Crick hypothesized that DNA replicates itself by “unzipping” along the hydrogen bonds joining A to T and C to G.This process would produce two opposite halves that could then serve as templates for the construction of new, complementary strands.This model of semiconservative replication conservative because each new molecule has one half of the former parent molecule-was later confirmed by the work of DNA进行复制是以拉链方式自我复制,产生的两个二分体分别为模板生成互补链,即半保留复制。并由Meselson和 Stahl验证。
In E.coli DNA replication begins with the formation of a bubblelike structure on the circular chromosome that is produced by replication forks.Studies of bacterial DNA replication have shown that a growing DNA chain lengthens only in the 5' to 3' direction(from the 5' carbon of one sugar to the 3' carbon of the next).The leading strand is synthesized continuously, while the lagging strand is synthesized in short stretches known as Okazaki fragments.The enzyme DNA polymerase links free nucleotides as they line up on the template formed by the original strand of the parent molecule.In eukaryotes DNA replication follows the same general principles as in prokarotes.On the long DNA molecules replication proceeds(in two directions at once)from hundreds or thousands of points of origin.大肠杆菌复制开始时形成泡样复制叉,链生长方向由5′向3′端,前导链连续生成,后随链由冈崎片段组成,由DNA聚合酶催化。真核生物复制与原核生物复制相似,但有几百到几千个复制原点(原核一般只有一个复制原点)。
课后作业:第一篇阅读材料 答案:1C,2C,3B,4A,5D,6D,7B
Glossary
one-gene-one-enzyme hypothesis 一基因一酶假说
The hypothesis that a large class of gene exist in which each gene controls the synthesis or activity of but a single enzyme.Since enzymes and other proteins whose syntheses are controlled by more than one gene are now known, this hypothesis has been replaced by the one-gene-one polypeptide hypothesis.one-gene-one-polypeptide hypothesis一基因一多肽假说 The hypothesis that a large class of genes exist in which each gene controls the synthesis of a single polypeptide.The polypeptide may function independently or as a subunit of a more complex protein.adenine 腺嘌呤
A purine base that is an essential constituent of the nucleic acids and also of such coenzymes as NAD and FAD.guanine 鸟嘌呤
A double-ring nitrogenous base molecule in DNA and RNA.It is the complementary base of cytosine.cytosine胞嘧啶
A single-ring nitrogenous base molecule in DNA and RNA.It is complementary to guanine.thymine 胸腺嘧啶
A single-ring nitrogenous base molecule of DNA but not RNA.It is complementary to adenine.purine 嘌呤
One of a group of nitrogenous bases whose parent compound has the formula shown.The two most abundant purines are adenine and guanine, which are constituents of nucleic acids and coenzymes.pyrimidine 嘧啶
A heterocyclic organic compound, C4N4N2 the fundamental form of pyrimidine bases.Some of these bases are constituents of nucleic acid.nucleoside 核苷
A purine or pyrimidine base attached to ribose or deoxyribose.The nucleosides commonly found in DNA and RNA are: cytidine, cytosine deoxyriboside, thymidine, uridine, adenosine, adenine deoxyriboside, guanosine, and guanine deoxyriboside.Note that thymidine is a deoxyriboside and cytidine, uridine, adenosine,andguanosine are ribosides.X-ray diffraction
X射线衍射
A technique for determining the arrangement of atoms in a crystalline substance by analysing the diffraction patterns produced when a narrow beam of X-rays is passed through the substance.X-ray diffraction has contributed to the elucidation of structure of many biological molecules, including some important macromolecules, e.g., DNA, haemoglobin, myoglobin.DNA double helix 双螺旋
The three-dimensional structure of doublestranded DNA.semiconservative replication 半保留复制
The method of replication of DNA in which the molecule divides longitudinally, each half being conserved and acting as a template for the formation of a new strand.replication fork 复制叉
A point at which the two strands of a DNA double helix are unwound and separated during replication.Okazaki fragment 冈琦片断
A short sequence of DNA that is the primary product of DNA polymerase during DNA replication.polymerase DNA 聚合酶
An enzyme that brings new DNA triphosphate nucleotides into position for bonding on another DNA molecule.Lesson Six(2学时)
The Origin and Diversity of Life
教学目的:使学生了解生命的起源和多样性及相关假说,使学生掌握相关专业词汇以及主要用法。教学重点:生物分类的组成及相关英语词汇的掌握。教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:5月10日 教学内容:
A Home for Life: Formation of the Solar System and Planet Earth The story of life's origins begins with the formation of the earth.The sequence of events that gave rise to our planet began, in turn, with the cosmic explosion physicists call the Big Bang.The sun at the center of our solar system condensed from a cloud of primordial matter roughly 5 billion years ago;the planets, including the earth, condensed about 4.6 billion years ago.The earth is composed of a number of layers: a solid crust, a semisolid mantle, and a largely molten(liquid)core that has a solid center.Basic physical features of Earth that may have made the emergence of life possible include the planet's size, temperature, composition, and distance from the sun.The major current hypothesis holds that life arose spontaneously on the early earth by means of chemical evolution from nonliving substances.生命起源于地球的形成。大爆炸是我们行星形成的开始。太阳在50亿年前生成,位于太阳系中心,行星,包括地球,在46亿年前生成。地球由多层组成:坚硬的地壳,半流体的地幔,一个很大的溶解中心中存在一个坚实的中心。地球的基本特征使生命起源成为可能,包括行星的大小,温度,组成以及离太阳的距离。当前主要假设认为,由非生命的化学物质进化过程自发产生了生命。The Emergence of life: Organic and Biological Molecules on a Primitive Planet Evidence for prelife stages of chemical organization comes from laboratory experiments that try to duplicate the physical environment and chemical resources of the early earth.These experiments, including the pioneering work of Miller and Urey, have successfully produced organic monomers including amino acids, simple sugars, and nucleic acid bases.The probable next step toward life was the spontaneous linking of such monomers into polymers such as proteinoids and nuclei acids.Current research suggests that likely sites for this polymerization were clay or rock surfaces.通过创造出地球早期的自然条件和化学资源条件,科学家在实验室中已经获得了化学有机体生命前阶段的证据。这些实验包括米勒等早期所做工作,成功地产出了有机单体,包括氨基酸,单糖,核酸碱基。这些单体自发的连接成多聚体,如类蛋白和核酸,使进入生命状态成为可能。这些聚合作用可能发生在泥土或岩石表面。
Researchers have found that, when energy is available to a system, they can generate three kinds of organic molecular aggregates.The Russian AleksandrOparin obtained polymer-rich droplets, called coacervates from solutions of polymers.Sidney Fox generated proteinoid microspheres from mixtures of amino acids and water.A third laboratory structure is the liposome, a spherical lipid bilayer that forms from phospholipids.A structure similar to one or more of these aggregates may have been the precursor of true cells.当一个系统获得能量时,可能发生3种有机分子的聚集。从多聚物的溶液中俄国科学家获得了富含小液滴的多聚物,即凝聚物。从氨基酸和水的混合液中Fox获得了类蛋白微球体。实验室第三个结构物质是脂质体,即由磷脂形成的球形脂双层结构。
Further steps in the appearance of cells on the earth included the development of RNA and DNA as biological information molecules.Evidence suggests that RNA, which can form spontaneously under conditions mimicking those of the early earth, was the first informational molecule.The discovery of RNA ribozymes-RNA that can act as an enzymelike catalyst suggests that such catalytic RNA also could have assembled new RNAs from early nucleotides.Certain catalytic RNAs can also carry out sexlike exchanges of pieces of RNA.RNA可能是地球早期形成的第一个贮藏信息的物质。在实验室模拟早期地球自然条件下其可自发形成。核酶的发现说明它可以催化早期核苷酸形成新的RNA。某些催化RNA具备类似于RNA 片段性交换的功能。Following the development of a lipid-protein surface layer and replicating RNA and DNA informational molecules, the events leading to the emergence of living cells would have included the origin of the genetic code;the sequestering of RNA or DNA into cell-like structures;and the development of metabolic pathways.接下来脂蛋白表层的形成,RNA的复制,DNA信息分子的形成,最终导致活细胞的出现,包括最初的遗传密码,RNA或DNA被包裹进细胞样的结构中;及代谢途径的建立。The Earliest Cells The oldest fossils that may represent living cells are found in rocks that are about 3.5 billion years old.The cells were probably anaerobic heterotrophs, with autotrophs arising much later.The first autotrophs produced their own nutrients and released O,-a metabolic by-product that had a crucial impact on later life forms.The resulting ozone layer in the earth's atmosphere reduced the penetration of ultraviolet light.As a result, cells would survive in shallow water and on the land surface.The increasing quantity of atmospheric oxygen also permitted the evolution of aerobic cells and cellular respiration, which in turn signaled the beginning of the global carbon cycle.Although the earliest cells were all prokaryotes, by about 1.5 billion years ago eukaryotes appeared.能说明活细胞存在的最古老化石大约有35亿年了。最早出现的细胞可能是厌氧异氧生物,自养生物很久后出现。最早的自养生物自己生产营养并释放氧气,这个新陈代谢副产品对后期生命的形成有一个深远的影响。臭氧层的出现减少了紫外线的渗透。结果,细胞就能够在浅水区和陆地上生存了。大气中氧气数量的增加使得需氧细胞进化并产生细胞呼吸,这预示着全球碳循环的开始。最早期的细胞都是原核生物,直到15亿年后,真核细胞才出现。The Changing Face of planet Earth Changes in land masses, the seas, and climate have greatly affected the evolution of life on the earth.The basic parts of the planet include a light, solid crust over a hot, semisolid mantle and an inner, partially molten core.Massive segments or plates of the crust move over the mantle in the process of continental drift.Over the past 500 million years, continental drift has sculpted the earth's crusts to produce the form and distribution of present-day continents.Climatic changes that greatly affected living organisms accompanied these plate movements;the period was marked by occasional waves of mass extinctions of living creatures.Organisms were also affected by periods of glaciation that followed variations in the earth's orbit and in the output of energy by the sun.大陆板快,海洋的改变,以及气候对地球生命的进化都有深远影响。地幔上大板快地壳的挤压形成大陆漂移。大陆漂移雕塑了地壳的外观,使现在大陆形成。伴随板块运动,气候改变对活有机体有深远影响。在特定时期的生物大量灭亡高峰是这个时期的见证。生物也受冰河期影响,在冰河期,地球轨道和太阳能的输出都发生了很大变化。
Taxonomy: Categorizing the Variety of living Things Biologists use the binomial system of nomenclature developed by Linnaeus to categorize the varieties of life on the earth.The system assigns each type of organism to a genus and species.Organisms are then further classified into higher taxonomic categories-family, order, class, division(plants), phylum(animals), and kingdom.Evidence from many subfields of biology, such as biochemistry and comparative anatomy, helps define species and higher taxa(taxon).And whereas species were originally defined in terms of morphological traits, today biologists generally use the criterion of a reproductively isolated population.生物学家利用林奈发展的双名法对生物分类。系统选定每个类型的生物进入属和种,然后将生物进一步分类更高级类别中,即科,目,纲,门,界。来自于生物化学和比较解剖学等亚生物学领域的证据有助于划分物种和更高级的分类单位,然而物种最初依据形态学特征进行分类的,今天生物学家大体上使用生殖隔离群体作为标准。
Taxonomy reveals a great deal about the evolutionary relationships among organisms.A clade is a taxonomic unit whose members are derived from a common ancestor.分类学揭示了物种间进化的大量关系。进化枝中的成员来自一个共同的祖先。The Five Kingdoms A phylogenetic tree is a graphic representation of evolutionary relationships.Your text uses a common five-kingdom arrangement: organisms are grouped into the kingdoms Monera, Protista, Fungi, Plantae, and Animalia.Although this system is a convenient organizational tool, the kingdoms are probably no true clades.进化系统树是进化关系的图解表现。教材中使用一个通用的5界:原核生物,原生生物,真菌,植物,动物。尽管这个系统是一个便利的组织工具,5界划分可能不是正确的进化枝。课后作业:第一篇阅读材料 答案:1B,2A,3B,4C,5A,6C
Glossary
Big Bang 大爆炸
An explosion producing a pressure oscillation of the order of a millibar or more at a distant point on the Earth.e.g., the eruption of Krakatoa in 1883.Large nuclear fusion explosions are comparable.crust 地壳
The crust of the Earth is the outer shell of the Earth, defined by its composition and the properties of some seismic waves.mantle 地幔
The part of the interior of the Earth between the crust and the core.core 核心
The core of the Earth is that part lying below the mantle.coacervate团聚体,凝聚层
A collection of organic macromolecules surrounded by water molecules that are aligned to fon-n a sphere.liposome 脂质体
A vesicle formed by the homogenization(emulsification)of phospholipids in dilute salt solutions.Liposomes are the prototypes of membrane-bound biologic structures.ozone layer 臭氧层
A layer of the atmosphere, about 20 to 50 km above the surface, which contains ozone produced by ultraviolet radiation.proteinoid类蛋白[质] A proteinlike structure of branched amino acid chains that is the basic structure of a microsphere.continental drift 大陆漂移
The theory that the present continents result from the break-up of a larger continent and have moved independently to their present positions.binomial system of nomenclature双名法
Uses two Latin names, genus and species, for each type of organism.genus 属(plural, genera)A unit used in the classification of plants and animals.A genus consists of a number of closely related species, and members of the same genus often have a number of obvious characteristics in common by which they can clearly be seen to be related.species 物种
A unit used in the classification of plants and animals.Ideally a species is defined as a group of organisms that interbreed with each other to produce fertile offspring.family 科
A unit used in the classification of plants and animals.A family consists of a number of closely related or similar genera or occasionally of only one genus.Family names end in-aceae or-ae in botany and in-ideae in zoology.order 目
A unit used in the classification of plants and animals.An order consists of a number of similar or closely related families or only on family.Names of orders end typically in-ales in plants and in-a in animals.class 纲
A group used in the classification of living organisms.A class consists of a number of similar or closely related orders or occasionally of only one order.Classes are usually large and easily recognized groups.division 门
A unite used in the classification of plants.A division consists of a number of classes, or occasionally of only on class, with certain important characteristics in common.phylum 门(复数 phyla)A unit used in the classification of animals.A phylum consists of a number of classes, or occasionally of only one class, with certain important characteristics in common, implying that all members are descended from a common ancestor.kingdom 界
In biology, a major category into which living material is classified.taxon 分类单位,分类群(复数 taxa)A unit of classification of any rank in the hierarchical scale.taxonomy 分类学
The study of the theory, procedure, and rules of classification of organisms according to the Similarities and differences between them clade 进化枝,分化单位
In a cladistic classification, organisms are placed into taxonomic groups called clades when they share characteristics that are thought to indicate common ancestry.Lesson Seven(2学时)
Fungi: The Great Decomposers
教学目的:使学生了解真菌的分类,典型真菌的结构特点,使学生掌握相关专业词汇以及主要用法。教学重点:真菌分类的组成及相关英语词汇的掌握。教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:5月17日 教学内容:
Characteristics of Fungi
The approximately 175,000 species of fungi include some of the simplest multicellular organisms.Fungi have a variety of lifestyles.They may be saprobes that decompose dead organic matter;they may be parasites which obtain nutrients from living hosts;or they may live in symbiotic relationships with algae or with the roots of higher plants.In spite of these variations, however, all fungi carry out extracellular digestion: they secrete enzymes that digest organic matter, and then they absorb the resulting nutrients.包括最简单的多细胞生物在内,真菌大概有175,000种。真菌有多种生命形式。他们可能是分解无生命的腐生菌;也可能是寄生菌;或者与藻类共生,或者与高等植物共生。不管如何变化,所有真菌都是细胞外消化。他们分泌酶消化有机物,然后吸收有效的营养物质。
Most fungi have the same basic body structure consisting of a main body or thallus composed of filaments called hyphae.In most species the walls of hyphal cells contain chitin.Hyphae in certain species may become specialized to form rhizoids, which serve as rootlike anchors, or they may become the feeding structures known as haustoria.Finally, hyphae may or may not be septate-having cross walls that segregate independent cells, each with at least one nucleus.Lower fungi are coenocytic;that is, they are one mass of cytoplasm that contains multiple nuclei.大多数真菌有同样的基本结构,即由菌丝组成的菌体。大多数真菌的细胞壁含有明角质。某些种类的菌丝可能特化形成假根,具有根样的固定作用,或者他们成为饲喂结构称吸器。菌丝或有细胞隔膜或没有细胞隔膜,但至少有一个细胞核。低级真菌是多核体的,即,一大团细胞质含有多个细胞核。
Hyphae grow and branch to form a filamentous network called a mycelium.Food is digested and absorbed at the tip of each hyphae;more hyphae are generated as this process continues.As a result, fungi may grow very rapidly.Growth depends on mitosis and the rapid manufacture of cytoplasm;fungal mitosis is unique in that it occurs within the nucleus.Hyphae from genetically distinct individuals may fuse to form a heterokaryon-a single cytoplasm with dissimilar nuclei.菌丝生长形成分支,进而形成网状结构称为菌丝体。在菌丝尖端,食物被消化并吸收;这个过程能持续产生更多菌丝。结果,真菌生长很快。生长靠有丝分裂和细胞质的快速产生。真菌的有丝分裂很独特,即它只发生在细胞核里。遗传学明显不同的菌丝个体融合形成异核体——同一个细胞质中含有不同的细胞核。As nonmotile heterotrophs, fungi must eventually be able to find new sources of nutrients.This function is fulfilled by spores, the fungal reproductive bodies.Spores may be home on aerial hyphae, which discharge spores into the air, and depending on the species they may haploid or diploid.There are two main categories of spores:(1)dispersal spores, which are usually short-lived and are produced in large numbers during active fungal growth;and(2)survival spores, which are usually produced in smaller numbers and at a time in the life cycle when the fungus is under some kind of environmental stress.作为不会移动的异养生物,真菌最终能够发现营养新资源的。这个过程由孢子来完成,即真菌的生殖体。孢子可能是在气生菌丝的中心,将孢子释放到空气中,依赖物种不同,可能是单倍体也可能是二倍体。有两种主要的孢子:(1)分散的孢子,通常生命期短,数量大,主要存在于活跃的菌丝生长阶段;(2)存活孢子,通常产生很少的数量,在生存压力条件下的一种生命循环。Classification of fungi As with some of the other groups you have studied, it is difficult to group fungi according to actual evolutionary relationships.In general, they are classified according to morphology, methods of reproduction, and modes of spore production.On the basis of these features, the single division of the kingdom Fungi, Mycota, is divided into six principal classes.对真菌依据实际进化关系进行分类是很困难的。总体来说,它们是依据形态学,生殖方式,孢子产生的模式来分类。基于这些特性真菌界的门被分成6个基本纲。
The lower fungi comprise the groups Chytridiomycetes, Oomycetes, and Zygomycetes.All lack septate hyphae and are commonly coenocytic;spores are formed by asexual means.Of the six fungal classes, only the oomycetes usually have a diploid vegetative state.Oomycetes and chytrids(sometimes called water molds)produce motile, flagellated spores in sporangia.They also produce gametes in gametangia;oomycetes are distinguished by their large, immobile egg cells.In fact, both these groups have such distinctive features that some biologists prefer to classify them as protists rather than fungi.Zygomycetes resemble the other two classes in this group but have nonmotile spores.They are also completely terrestrial, and some form mycorrhizal associations with plant roots.低级真菌包含壶菌,卵菌纲和接合菌。所有缺乏隔膜的菌丝是通用的多核细胞的;孢子通过非性方式产生。只有卵菌纲通常有二倍体的营养状态。卵菌纲和壶菌在孢子囊中产生能动的带鞭毛的孢子。在配子囊中产生配子;卵菌纲具有非寻常大的静止的卵细胞。实际上,这两大群具有不同的特征,生物学家宁愿把它们归为原生动物而不是真菌。接合菌与其它两纲相似,但它的孢子不会动。它们完全是陆生的,一些菌根与某些植物的根形成共生关系。
The higher fungi include the class Ascomycetes, the largest class of fungi.Most ascomycetes are either saprobes or parasites.Asexual reproduction produces spores called conidia, which develop on the tips of specialized aerial hyphae.In the ascomycete sexual cycle, hyphae of different mating strains fuse, giving rise to ascospores that form in a small, saclike ascus.Groups of asci form fruiting bodies.Ascomycetes of interest to humans include truffles, yeasts, and Penicillium species.高级真菌包括子囊菌纲,最大的真菌纲。大多数子囊菌要么是腐生菌,要么是寄生菌。非性繁殖产生的孢子称分生孢子子实体,其依赖特化的气生菌丝尖。在子囊菌性循环过程中,不同的菌丝通过株融合进行匹配,产生的子囊菌存在于小类子囊中。子囊群形成果实体。对人类有利的子囊菌包括块菌,酵母和产青霉素菌。
Most members of the class Basidiomycetes—the second group of higher fungi form visible fruiting bodies.A prime characteristic distinguishing basidiomycetes from ascomycetes is the dense mass of dikaryotic hyphae called the basidiocarp-the “mushroom” seen on damp lawns and the forest floor.Club-shaped basidia, each bearing four haploid basidiospores, line the surfaces of the gills on the underside of the mushroom cap.Members of this group undergo both sexual and asexual reproductive processes at different times in their life cycle, and in response to varying environmental influences.纲中大多数菌为担子菌,第二大类高级真菌,能形成可见的果实体。担子菌与子囊菌相比,最基本不同是它具备浓密的双核菌丝,称担子果。棒形担子,每个都含有4个单倍体的担子孢子,线形地排列在蘑菇帽下的菌褶表面。大多数成员有性和非性繁殖两种,在不同生命循环中有不同形式,并依据环境变化而变化。The class Deuteromycetes, or Fungi Imperfecti, includes a variety of fungi that lack modes of sexual reproduction.Most are known to reproduce asexually by means of conidia.Deuteromycetes important to humans include those used to ferment soybeans and rice to make soy sauce and sake respectively, and those responsible for producing citric acid and the highly dangerous aflatoxin.半知菌纲,包括大量无性繁殖的真菌。分生孢子完成非性繁殖。对人类很重要的半知菌纲包括发酵大豆成酱油和大米发酵成清酒的菌类,它们也产生柠檬酸和有毒的黄曲霉毒素。Lichens: The Ultimate Symbionts Lichens are composite organisms in which about 90 percent of the lichen mass consists of one species of fungus, while the remaining 10 percent is made up of one or two species of algae.The algal portion of the lichen provides the fungal portion with essential nutrients, while the presence of the fungal component may enable the alga to exploit an otherwise unavailable ecological niche.Lichen fungi are usually ascomycetes, although the other two higher fungi are sometimes found in lichens.Lichens have a number of remarkable features, including their ability to become almost completely desiccated without drying and their ability to absorb inorganic nutrients.Reproduction in lichens is not well understood.地衣是复合生物,大概90%的地衣团由一种地衣组成,10%含有一两种藻类。藻类为真菌提供必要的营养,真菌为藻类提供了难得的小生态环境。地衣真菌通常是子囊菌,有时在地衣中也能发现其他两类真菌。地衣有大量的显著特征,包括在几乎脱水条件下仍能吸收无机养分。地衣繁殖方式还不清楚。Fungal Evolution The various fungi may have arisen independently from prokaryotes, since some evidence suggests that ascomycetes and basidiomycete did not evolve from known lower forms.However, all fungi do show the same dependence on nutrients produced by plants, animals, or algae.各种真菌可能都独立进化于原核生物,有证据表明,子囊菌和担子菌没有进化。但所有真菌都依赖由植物,动物或藻类产生的营养。课后作业:阅读材料一 答案:1B,2B,3A
Glossary
saprobe 腐生菌
An organism that lacks the ability of photosynthesis, and lives on dead or decaying organic matter, a saprophyte.hyphae 菌丝(复数hypha)
Fungal filaments that develop from the growth of germinating spores.They are the fundamental elements of a mycelium.rhizoid 假根
One of many uni-and multicellular filamentous outgrowths that are produced by some algae and by the gametophytes of bryophytes and pteridophytes and function as roots.haustorium吸器(复数haustoria)A specialized structure of some parastic plants(e.g., dodder, mistletoe etc.)which penetrates into the vascular bundles of the host plant to obtain nourishment.mycelium 菌丝体(复数mycelia)The tangled mass of hyphae that forms the vegetative body(sometimes terined a thallus)of a fungus.heterokaryon异核体
In somatic cell genetics, the state when two cells have ftised but their nuclei have not yet fused septate有隔膜的,分隔的
Divided by a septum.sporangium 孢子果,孢子囊(复数 sporangia)A cell within which spores or sporelike bodies are home.Generally, it is an asexual structure of certain fungi gametangium配子囊(复数gametangia)A gamete-producing structure or sex organ in plants, i.e.an antheridium, oogonium, or archegonium..ascomycetes子囊菌
A female reproductive structure of some ascomycetes in which plasmogamy occurs prior to ascus formation.conidium分生孢子子实体(复数conidia)An asexual spore of certain fungi that is abstracted from the tip or the side of special hyphae called conidiophores.Conidia may consist of one cell or of several cells;in the latter case the septa may be longitudinal, transverse, or mixed.ascus子囊(复数asci))The characteristic structure producing sexual spores in the Ascomycetes.basidiomycetes担子菌纲
A group of mycelial fungi(Eumycophyta)whose sexual reproduction results in the formation of basidia, which(except in the rusts and smuts)are home on basidiocarps.basidiocarp担子果
A fruiting body of the higher basidiomycete fungi.Basidiocarps are the most obvious manifestations of these fungi and include mushrooms, toadstools, and similar bodies.basidium担子(复数basidia)
The characteristic structure producing sexual spores in the Basidiomycetes.Fungi Imperfecti(Deuteromycetes)半知菌属,半知菌亚门
A group of fungi with septate mycelia in which sexual reproduction is either lacking or is not known.Many of these fungi are of great importance as they cause diseases in plants, animals, and man.lichen 地衣
Thallophyte plants composed of a fungus and an alga in such close symbiosis that they form a vegetative plant body that is morphologically different from either of the constituents.Lesson Eight
Animal Development
教学目的:使学生了解动物的生育过程,胚胎发育的结构特点,使学生掌握相关专业词汇以及主要用法。教学重点:动物发育过程及相关英语词汇的掌握。教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:5月24日 教学内容:
Production of Sperm and Eggs
In sexually reproducing organisms males and females produce sex cells, known as gametes.These are swimming sperm in males and ova(eggs)in females.在性繁殖过程中,生物的雄性和雌性产生性细胞,称配子。雄性是能够游动的精子,雌性是卵子。The process of sperm production, spermatogenesis, takes place in testes.The sperm originate in gonial cells(spermatogonia)in the walls of seminiferous tubules.Spermatocytes produced by mitosis in spermatogonia divide meiotically to generate haploid spermatids.The mature sperm has a tail, a nucleus containing haploid chromosomes, and a front end with an acrosome, the storage site for enzymes that will aid fertilization.精子产生过程,即精子发生在睾丸中。精子产生于输精管壁的性母细胞(精原细胞)。精原细胞经有丝分裂再减数分裂产生单倍体精子细胞,即精母细胞。成熟精子有尾部,单倍体染色体组,头部有顶体,内部储存酶类,有助于受精。
Ova, which are produced during oogenesis, are generated in gonial cells(oogonia)of the female's ovaries.Oocytes then enter a stage of arrest in early meiosis.At a species-specific later point, a final ripening(ovulation)and the first meiotic division occur.A second meiotic division, followed by development of the embryo, takes place if the egg is fertilized.在卵子发生过程中,由卵巢中的性母细胞产生。卵母细胞进入减数分裂的抑制阶段。第一次减数分裂产生一个成熟卵。如果卵受精,那么第二次减数分裂伴随胚胎的发育。
Eggs vary greatly in size from species to species and have complex structures.Virtually all developing animal ova are surrounded by helper cells, either follicle cells or nurse cells.Depending on the species, eggs also store varying amounts of yolk, a reservoir of nutrients produced by digestive-gland cells in the mother's body.Finally, follicle cells or cells of the maternal oviduct provide protective coatings for the egg, including albumen(egg white)and various types of outer membranes and shells.品种间卵的大小变化很大,并且有复杂的结构。实际上,所有发育过程中的卵都辅助细胞环绕,要么是滤泡细胞,要么是抚育细胞。依赖物种的不同而不同,卵黄贮备也不同,即由母体消化腺细胞产生的营养储备。最后,滤泡或母体输卵管细胞产生保护性的卵膜,包括清蛋白和各种外部膜及壳。
Frog oocytes have served as model systems for studies of oocyte development.During maturation they produce huge numbers of ribosomes through gene amplification.Large quantities of mRNA may also be made and stored.蛙卵母细胞作为卵母细胞发育的研究系统模型。在成熟过程中,通过基因扩增产生大量的核糖体。同时也产生和储备了大量的mRNA。Fertilization: Initiating Development Fertilization unites male and female gametes and initiates development.In some species fertilization is external;in others(including most terrestrial animals)it takes place internally.The first contact of the sperm head with the egg's jelly coat triggers the acrosome reaction, in which enzymes are released to digest a hole through the egg's protective layers, and the plasma membrane of the sperm is brought into position to bind to the ovum's surface.After fusion of the egg and sperm plasma membranes, the haploid male nucleus with its chromosomes moves into the egg cytoplasm.Fusion also triggers the egg's final meiotic reduction divisions.When sperm and egg nuclei unite, the two sets of chromosomes mingle to create a diploid set.The fertilized egg is now a zygote.雌雄配子结合作用称受精作用,发育开始。某些物种中,是外部受孕;另一些物种,包括大部分陆生动物,是内部受孕。当精子和卵子的胶状膜发生接触时,触发了顶体反应。释放多种酶而将卵保护膜消化出一个洞。精子的原生质膜与卵子的表面连接起来。精卵原生质膜融合后,单倍体雄性核进入卵细胞质。融合也触发了最后的减数分裂。当精卵核结合时,两套染色体混合产生一二倍体,即受精卵。
The egg's cortical reaction serves as a barrier to the entry of more than one sperm.Initially, there is a temporary change in the egg's electrical state, and the egg cell is activated.The final stage of the reaction, the rapid elevation of the fertilization membrane, prevents further sperm penetration.卵皮层阻止其他的精子进入,充当壁垒作用。开始时,卵电位发生暂时变化,卵细胞被激活。反应最后阶段,受精卵的膜快速隆起,阻止更多精子进入。
In some species fertilization is not necessary.Instead, parthenogenesis takes place: the egg is spontaneously activated and proceeds to normal embryonic development.对某些物种而言,受精不是必须的。孤雌生殖,即卵自发地被激活并进入正常的胚胎发育过程中。Cleavage: An Increase in Cell Number Cleavage, the major developmental event immediately following fertilization, is a special form of cell division(mitosis).Cleavage produces a blastula, a sheet of cells rounded into a sphere that in most species surrounds a cavity.In the process, the single-celled zygote is divided into many small cells, and yolk, mRNA, ribosomes, and other materials arc distributed to each cell in precise ways.The cells of the blastula, called blastomeres, also each receive a full diploid set of chromosomes.受精后,立即发生卵裂,细胞有丝分裂的特殊过程。卵裂产生一个囊胚,形成的细胞壁球形排列形成一个空腔。在这个过程中,单细胞的受精卵分裂成许多小细胞,卵黄,mRNA,核糖体和其他物质被精确分配到每个细胞中。这些囊胚细胞,称卵裂球,每个细胞都有一套二倍体染色体组。
There are different patterns of cleavage in different species.The amount of yolk present in the egg is a major factor in determining the pattern: in species having little yolk(such as mammals)the zygote cleaves completely through, forming cells that are roughly equivalent in size.In frogs, in which the egg has somewhat more yolk, cleavage proceeds more rapidly in regions of the embryo having less yolk.In bird eggs the yolk is so massive that cleavage divisions are restricted to a tiny area of cytoplasm.不同物种,卵裂方式不同。决定因素主要取决于卵黄的含量。含有少量卵黄的物种(例如哺乳动物),合子分裂得很彻底,子细胞大致平均分裂。蛙卵,卵黄稍微多点,在胚胎的卵黄较少区域发育更快些。鸟卵卵黄很大,卵裂被限制在细胞质很小区域内。
In many species the precise distribution to blastomeres of molecular determinants in the cytoplasm is crucial to proper development of different cell types in the embryo.In mammal and bird species the fate of cells is determined by the position of a cell late in cleavage.细胞质中分子遗传因素精确分配到卵裂球中,对许多物种而言,是发育成胚中不同类型细胞关键所在。对哺乳动物和鸟类而言,细胞的命运最终由细胞分裂后所处的位置决定的。Gastrulation: Rearrangement of Cells(原肠胚:细胞重排列)
The rearrangement of the blastula into a three-dimensional organism with inner, middle, and outer layers occurs during gastrulation.The resulting gastrula consists of an outer ectoderm, an inner endoderm, and a mesoderm layer positioned between them.在原肠胚形成过程中,囊胚重新排列,形成包括内层,中层,外层的三围组织。最终原肠胚由一个外肠胚,内肠胚,和一个中肠胚构成。
Each layer gives rise to specific tissues during embryonic development.A variation in gastrulation, involving the movement of cells into endodermal and mesodermal positions through the thickened primitive streak, arose in reptiles and can still be seen in bird and mammalian embryos, lending support to the theory that birds and mammals evolved from reptiles.每个胚层产生特殊的胚胎组织。密实的原肠胚通过细胞运动进入内胚层和中胚层,爬虫,鸟,哺乳动物的胚胎都如此。因此提出这样的理论,鸟类和哺乳动物是由爬虫进化而来的。Organogenesis: Formation of Functional Tissues and Organs The organs and tissues of the embryo arise during organogenesis as cells inside the embryo and on its surface become specialized.Organogenesis actually includes two closely linked processes, morphogenesis and differentiation.During morphogenesis cells and cell populations change shape: an example is neurulation in vertebrate embryos, in which the edges of the flat neural plate fold upward and fuse, forming the beginnings of the hollow brain and spinal cord.During differentiation cells mature so that they may perform separate functions.This maturation may include taking on a function-related shape, such as the long, spindly shape of skeletal-muscle cells.Cell differentiation also results in responsiveness-the ability of a cell to be regulated within the organism through the action of hormones, neurons, and other signals.胚经过内部细胞和表面细胞特化后,器官形成,发育成器官和组织。器官形成实质上包括两个联系紧密的过程,即形态发生和分化。在形态发生期间,细胞和细胞群体形状发生改变:例如,脊椎动物的神经胚,扁平神经板的边缘向上折叠并融合,是中空大脑和脊髓神经形成的开端。在分化期间,细胞成熟,执行各自功能。成熟包括功能相关的成型过程。例如,细长的骨骼肌肉细胞。细胞分化也产生应答能力,即细胞受生物体内激素,神经和其他信号的调控过程。Embryonic Coverings and Membranes The embryos of land vertebrates are enclosed within four extraembryonic membranes that afford protection while still permitting the exchange of gases, nutrients, and other materials.脊椎动物的胚胎被4层膜包被,起保护作用,但仍能交换气体,营养和其他物质。Growth: Increase in Size Growth in embryos is largely due to an increase in the number of cells rather than to an increase in the size of individual cells.In many species the extent of embryonic growth is limited by the availability of food(yolk).In animals that develop entirely free of the maternal body, such as frogs and insects, the embryo give rise to a larval stage that can feed itself and later undergo metamorphosis to attain the adult stage.In many species the most spectacular growth phase takes place during the juvenile and adolescent phases of the life cycle.Actual growth generally stops once the organism reaches its typical adolescent phases of the life cycle.Actual growth generally stops once the organism reaches its typical adult size, although replacement of dead cells may continue.胚的生长很大程度取决于细胞数量的增加而不是单个细胞大小的改变。在大多数物种中,胚的生长是受卵黄的量限制的。在动物细胞中,完全依赖于母体,例如蛙和昆虫,胚产生幼虫状态,后来经历变态而进入成年状态。在许多物种中,在少年和青春期,发生特别显著的生长。一旦细胞进入成年状态和成年大小,生长就停止了,尽管死细胞的替代不断发生。
A special type of growth, regeneration of lost body parts, can take place in adults of some species.Prior to such regeneration cells in stump tissue undergo dedifferentiation.They lose their functional phenotype, divide rapidly, and generate a population of cells that will regenerate the lost part.Compensatory hypertrophy is a different, temporary growth response in which residual tissue increases in mass and cell number: cells undergo mitosis but do not dedifferentiate.一个特殊类型的生长,再生失去的部分躯体,发生在某些物种的成体中。在再生之前,残肢组织细胞经历了去分化过程。他们失去功能表型,快速分裂,产生细胞群来再生失去的部分。代偿式肥大是一个不同的,暂时的生长应答过程,残余组织在体积和细胞数量上增加:细胞经历了减数分裂,但没有去分化过程。Aging and Death: Final Developmental Processes Aging is an ongoing, time-dependent developmental process in which body parts deteriorate.Proposed causes include the degeneration of collagen(the fibrous proteins of the connective tissues)and limits on the number of times cells can divide.Other theories focus on a decline of the immune system or on the accumulation of lipofuscins(aging pigments).老化是一个持续过程,随时间发育,身体部分恶化。可能原因包括胶质的退化(纤维蛋白)和能分裂活细胞的限制。另外理论认为,免疫系统的免疫下降或脂褐素的堆积造成的。课后习题:阅读材料一
Glossary
sperm精细胞
Cells that develop from the spermatids by losing much of their cytoplasm and developing long tails;the male gamete.ovum 卵,卵子(复数,ova)
An unfertilized non-motile female gamete.In many animals it is produced in the ovary.spermatogenesis 精子发生
The specific name given to the gametogenesis process that leads to the formation of sperm.oogenesis 卵子发生-The specific name given to the gametogenesis process that leads to the formation of eggs.ovaries 卵巢,子房
The female sex organs the produce haploid sex cells, the eggs or ova.yolk 卵黄,蛋黄
The store of food material, mostly protein and fat, that is present in the eggs of most animals oviduct 输卵管
The tube(fallopian tube)that carries the primary oocyte to the uterus.gene amplification 基因扩增
A temporary dramatic increase in the numbers of a particular gene in a genome during one developmental period.fertilization 受精
The joining of haploid nuclei, usually from an egg and a sperm cell, resulting in a diploid cell called the zygote.Zygote受精卵
A diploid cell that results from the union of an egg and a sperm.acrosome reaction 顶体反应
That series of observable, structural changes undergone by a sperm when in the vicinity of an ovum in the oviduct.Specifically, many openings appear in the sperm head membrane, through which the contents of the acrosome appear to be released.parthenogenesis ['pa:einE]u'd3enisis]单性生殖,孤雌生殖
Reproduction in which eggs develop normally without being fertilized by a male gamete, producing an individual usually genetically identical to the parent.cleavage 卵裂
The mitotic division of the zygote that occurs immediately after fertilization and produces a ball of smaller cells without an overall increase in size.blastula 囊胚,囊胚泡
The stage of the early animal embryo that succeeds cleavage and precedes gastrulation.A blastula is usually made up of a hollow ball of cells, with a wall one to several cells thick;the central cavity is the blastocoel.blastomere卵裂球
One of several small cells formed from an animal zygote during cleavage.gastrulation 原肠胚形成
The process in the animal embryo by which a blastula is converted into a gastrula, with the laying down of the germ layers.gastrula 原肠胚
The stage in the development of animal embryos that follows the blastula and results from gastrulation.The cells of a gastrula are differentiated into the germ layers and the central cavity opens to the exterior by the blastopore.ectoderm 外胚层,内层
The outermost of the germ layers of metazoan embryos.It develops mainly into epidermal tissue, the nervous system, sense organs, and(in lower forms)the nephridia.endoderm 内胚层,内层
The innermost of the germ layers of metazoan embryos.Mesoderm中胚层,中层
The middle layer of the three germ layers of triploblastic animal embryos.It develops into cartilage, bone, muscle, blood, kidneys, and gonads.primitive streak 原肠胚 A longitudinal band of embryonic mesodermal cells that develops within a dorsal groove along the length of the gastrula of mammals and birds.organogenesis 器官形成 The formation of organs.morphogenesis形态发生,形态建成
The developmental processes leading to the characteristic mature form of an organism or part of an organism.differentiation 分化,鉴别
The complex of changes involved in the progressive diversification of the structure and functioning of the cells of an organism.For a given line of cells, differentiation results in a continual restriction of the types of transcription that each cell can undertake.neurulation神经胚形成
Developmental stage in an embryo during which the cells differentiate into the brain and spinal cord.metamorphosis 变态
The transformation from larval to adult form.regeneration 再生
The replacement by an organism of tissues or organs that have been lost.dedifferentiation 去分化,脱分化
The loss of differentiation, as in the vertebrate limb stump during formation of a blastema.compensatory hypertrophy 代偿式肥大 See regeneration.Lesson Nine
The Origin of Species
教学目的:使学生了解物种起源相关理论,使学生掌握相关专业词汇以及主要用法。教学重点:物种起源相关理论及相关英语词汇的掌握。教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:5月31日 教学内容:
How Biologists Define a Species Modern biology generally define a species as group of actually or potentially interbreeding populations that is reproductively isolated from the such groups.Members of a species can interbreed with each other, but they cannot breed with organisms belonging to another species.One advantage of the standard of reproductive isolation is that it is very precise.Notice, however, that it can only be applied to organisms that reproduce sexually.Asexual reproducers, including most prokaryotes, many plants, and some animals, must be classified into species on the basis of physical(biochemical or morphological)traits.现代生物学大体将物种定义为实际上的一群或潜在的杂交群体,即从这个群体隔离繁殖的后代。种族中个体可以互相交配,但种间不能。这种繁殖隔离的一个优势是很精确。但仅适用于性繁殖的生物。非性繁殖,包括大多数原核生物,许多植物,某些动物,需要通过自然特征进行归类。Preventing Gene Exchange Two general types of mechanisms operate to block the exchange of genes between individuals of related groups.The first general type is made up of prezygotic isolating mechanisms that prevent the formation of zygotes.Prezygotic isolation falls into two categories: ecological and behavioral.In the first case, two related group may become adapted to slightly different environments-perhaps varying soil types or food sources.Over time, these genetic differences become so great that successful cross-fertilization can no longer take place.In behavioral isolation, related groups evolve differing behaviors such as specific mating rituals-that restrict the exchange of genes to members of the same group.两种基因型机制阻碍了相关群体中个体的基因交换。第一种基因型由前合子机械隔离机制阻止合子的生成。前合子隔离分两类:生态学的和行为学的。第一种情况,两个相关群体可能分别适应稍微不同的环境,如土壤类型或食物来源的变化。长时间,这些遗传差异变得很大而很难异体受精。而行为学隔离,相关的群组进化成不同的行为方式,例如,结婚仪式,从而限制了同群成员基因交流。
Sometimes the differences that produce prezygotic isolation involve mechanical isolation.That is, mating is physically impossible between members of different species because genitals of males and females are structurally incompatible or because molecules on the surfaces of sperm and egg fail to bind.A final type of prezygotic mechanism is temporal isolation, in which time-related environmental cues that trigger reproductive processes are different for related species.有时,产生前合子隔离的差异涉及了隔离机制。即,由于生殖器结构不匹配或精卵分子表面不结合而使不同种群成员间不能自然结合。最后一类前合子机制是暂时隔离,与时间有关的环境因素触发了相关物种的不同繁殖过程。
In postzygotic isolating mechanisms mating occur, but the resulting hybrid organism is inviable or sterile.In a special case of hybrid sterility termed hybrid breakdown, the second and subsequent generations after a cross show reduced reproductive success.Contrast this fact with the very different outcome of crossbreeding between two genetically distant members of the same species, where the result is often heterozygote advantage(hybrid vigor).在合子后隔离机制中,匹配可以进行,但或不产生杂种或杂种不育。杂种不育在某些特殊情况下,是指第二代或以后几代显示出杂交繁殖能力的降低。正是同种远基因成员间的杂交产生不同的结果,而产生杂种优势。
Populations of a species that are spread out over a broad geographical range are often arrayed in a cline-a gradual change in one or more characteristics as each population evolves adaptations to its own local environment.Along a cline, subspecies with distinct characteristics may arise.Often, individuals at either end of a cline are reproductively isolated.地域上分布很广的种的群体中,经常存在变异群,因为适应当地的环境,每个群体逐渐产生一个或多个与众不同的特点。在变异群中,带有明显特征的亚群可能产生。通常,在两个变异群中的个体是繁殖隔离的。Becoming a Species: How Gene Pools Become Isolated Ernst Mayr's model of allopatric speciation proposes that species can originate in a two-stage process.In the first stage, populations of existing species are separated by a physical or geographical barrier.As a result, over time genetic differences leading to pre-or postzygotic isolation arise between the two groups.In the second stage, the diverged populations may again come into contact.If this happens, speciation becomes complete through the action of natural selection.异地物种形成模型认为,物种可能起源于两个阶段。第一阶段,已经存在的物种群体可能由于自然或地理屏障被隔离。结果,长时间后,在两个群体间遗传差异导致前合子或后合子隔离的产生。第二阶段,这些趋异群体可能再次接触,物种发生可能通过自然选择发生。The Genetic Bases of speciation The extent of differences between populations that are diverging into separate species or between species that have already diverged is represented by a statistic called genetic identity-the relative proportion of the same structural genes present in members of groups being compared.In general, biologists believe that the genetic events leading to speciation take place gradually.Once a new species has arisen, it tends to diverge genetically from related species at a more rapid pace.In some cases, such as the primate order, major differences in body form are not reflected by corresponding divergences in structural genes.This has led Biologists to hypothesize that small changes in regulatory genes may account for many of the large-scale changes responsible for sepciation and the origin of higher taxonomic groups.能够趋异的群体或已经趋异的物种,他们之间差异的扩大,由一个稳定的遗传识别代表。即在可比群体成员中相同基因所占相关比例。大体而言,生物学家相信,遗传导致的物种形成是逐渐发生的。在某些情况下,身体主要差别并不能反映结构基因的趋异,生物学家因此提出,调控基因很少的改变可能导致很大规模物种改变和更高分类学上群体的产生。
One mechanism that may rapidly split populations genetically is polyploidization—the sudden multiplication of an entire complement of chromosomes.This can result in sympatric speciation, in which new species arise even though no geographical isolation has taken place.A phenomenon similar to polyploidization involving the rearrangement of chromosomes has been proposed to explain the evolutionary origin of giant pandas.Clearly, species can originate in a variety of ways.遗传学上可以快速分离群体的一个机制是多倍体,一个完全互补染色体组的突然倍增。结果导致同域物种形成,即使没有地理隔离也会产生新的物种。与多倍体相似的一个现象是染色体重排,可以解释巨大熊猫的进化起源。显然,物种可以以多种方式进化。Explaining Macroevolution: Higher-order Changes The changes that generate species are sometimes termed microevolution;those that produce the major phenotypic differences that separate genera, classes, orders, and so on are termed macroevolution.Some lines of descent can be traced by studying the fossil record.In other cases relationships must be inferred by comparison of related living organisms.When lines of descent over evolutionary time are constructed, the result is a phylogeny.遗传物种的改变有时称微进化;那些产生很大差异用来区分属,纲,目的表型变化称大幅进化。某些品系的后代可以通过化石追根溯源。而其他相关性可以通过现存活体的比较来推论。当品系后代以进化钟构建时,形成系统发育树。
The rationale for building a phylogeny is simple: it assumes that similarities in body structure, biochemistry, reproductive strategies, and other features of organisms can be used to trace lines of common descent.The process is complex because evolution proceeds in different patterns.In cases of parallel evolution, two or more lineages evolve along similar lines.In convergent evolution, very distantly related lineages become more alike as similar adaptations take hold in response to demands of the environment.Thus similar structures in different organisms may reflect homology(derivation from a common ancestor)or analogy(independent origin of structures used for similar purposes).建立系统发育树的基本理论很简单:把身体结构,生物化学,繁殖策略以及其他特征相似的生物划分进同一个品系。这个过程很复杂,因为进化经历不同模式。就平行进化而言,两个或更多的血统沿相似品系进化。在相似生存条件下,亲源关系很远的血统也可能更相似。不同生物间的相似结构可能说明它们具有同源性。
One of the most common evolutionary patterns that can be constructed from the fossil record is divergent evolution or radiation.It is represented by the branching and rebranching of a single line.Another common feature of evolution is extinction-the complete loss of a species or group of species.Mass extinctions have occurred at least five times in the earth's history.从化石证据构建的最普通进化模式是趋异进化。由分支和次级分支的简单线条代替。另一个进化的共同特征是灭绝。地球历史中至少发生过5次大规模的灭绝。
Gaps in the fossil record have led some paleontologists to propose the punctuated equilibrium theory of evolution.The theory holds that evolution proceeds by spurts-radical changes over short(in geological time)periods of time-with intervening periods of equilibrium.The theory is controversial and tends not to be supported when an abundant fossil record is available.化石证据上的断代使古生物学家们提出间断平衡进化理论。这个理论认为进化在短期内经历了根本突变,中间又介入均衡阶段。这个理论很有争议,一旦发现丰富的化石证据,理论就难支撑了。The Role of microevolution in Macroevolution Biologists have no certain answers to a number of questions about large-scale evolutionary changes.These questions range from whether novel higher taxa result from as-yet undescribed radical genetic processes, to whether known processes such as genetic drift and small gene changes can plausibly account for the evolution of new genera, families, and orders.Investigators are exploring these areas using traditional methods as well as the newer techniques of molecular biology.生物学家还无法回答关于大规模进化的许多问题。许多问题是新类别的物种可能起源于还不确定的遗传过程,或者知道遗传过程,例如,遗传漂移和少量基因的改变可能是新属,科,目产生的原因。科研工作者不但利用传统方法对这些领域进行研究,还利用分子生物学新科技。Glossary
hybrid sterility 杂种不育性
The failure of hybrids between different species to produce viable offspring.cline 梯度变异,变异群
A smooth gradation of characteristics from one end of the range of a species to the other, usually brought about by gradients of climate, soil, or other environmental variables.allopatric speciation
异域物种形成,异地物种形成
The development of distinct species through differentiation of populations in geographic isolation.sympatric speciation
同域物种形成,同地物种形成
Speciation that follows after ecological, behavioral, or genetic barriers arise within the boundaries of a single population.This can happen instantaneously, as when polyploidy arises in a type of flowering plant that can self-fertilize or reproduce asexually.microevolution 微进化,种内进化
Changes in allele frequencies brought about by mutation, genetic drift, gene flow, and natural selection.macroevolution 宏观进化,大进化,种外进化
The large-scale patterns, trends, and rates of change among groups of species.phylogeny 种系发生,系统发生,系统发育
Evolutionary relationships among species, starting with most ancestral forms and including the branches leading to their descendants.parallel evolution平行进化
The evolution of organisms that were originally very similar and have both evolved in the same direction.(Contrast with convergent evolution)convergent evolution
趋同进化
An evolutionary pattern in which widely different organisms show similar characteristics.Homology 同源性,同种性,同系性
A similarity between two structures that is due to inheritance from a common ancestor.The structures are said to be homologous.(Contrast with analogy)analogy 相似,同功
A resemblance in function, and often appearance as well, between two structures which is due to convergence in evolution rather than to common ancestry.(Contrast with homology)divergent evolution 趋异进化
A basic evolutionary pattern in which individual speciation events cause many branches in the evolution a group of organisms.extinction 灭绝,熄灭,消失
In genetics, inhibition of the expression of differentiated properties in hybrid cells from differentiated and undifferentiated parental cells.punctuated equilibrium 间断平衡
Evolutionary theory that holds that morphological changes occur rapidly in time;during speciation these changes occur in small populations with the resulting new species being distinct from the ancestral form.After speciation, species retain much the same form until extinction;distinct from the phyletic gradualism theory.Lesson Ten
The Ecology of Populations
教学目的:使学生了解物种群体生态学相关理论,使学生掌握马尔萨斯人口理论及相关专业词汇和主要用法。
教学重点:马尔萨斯人口理论及相关英语词汇的掌握。教学难点:专业英语词汇的记忆
讲授方法:以学生翻译为主,老师讲解相关专业知识辅助学生理解 授课时间:5月31日 教学内容:
Population Growth
Populations-groups of individuals belonging to the same species-all have three very significant statistical characteristics: per capita birth rate or natality;per capita death rate or motality;and number of individuals per unit area or density.种群中的每个个体都属于同一个物种,具有三个非常显著的统计学特征:出生率;死亡率;种群密度。As first described by Malthus, a population theoretically can grow exponentially(geometrically)if there are no limits on resources such as food or hiding places and no predation(ac of population growth is represented by an exponential growth curve.The condition exponential growth rarely occur in nature, however.The finite levels of resources in any environment set an upper limit to population size—termed carrying capacity(K)—that can be reached but never long exceeded.A logistic growth curve plots the leveling-off of growth when population size reaches equilibrium with available resources.马尔萨斯首次阐述了人口理论,他指出,如果没有类似于食物,庇护所等资源的限制,没有被捕食,群体总量的增长符合指数或几何关系。即指数生长曲线。但,这种指数生长在自然界中很少发生。环境中有限的资源限制了群体规模,即环境的容纳量,只能接近而不能超过。当群体规模接近可获得资源的最大平衡态时,逻辑生长曲线呈现负增长。When resource limits are approached or exceeded, time is required for the birth rate to fall and for the death rate to rise.This response time is known as reproductive time lag.It is one reason for the fluctuations in numbers that are seen in every population.In many natural populations, carrying capacity(and hence population size)fluctuates seasonally.If a population drastically exceeds the carrying capacity of its environment temporarily, damage may occur that permanently lowers environmental carrying capacity.当接近或超过资源限制时,出生率下降,死亡率升高。这段时期称繁殖滞后时期。这种群体数量的波动存在于每一个群体中。在自然群体中,群体数量随季节波动。若暂时超出环境的容纳量,可能造成对环境持久的伤害而保持很低的容纳量。
Besides environmental carrying capacity, a population's age structure and reproductive strategy also affect the rate at which the population grows.Age structure reflects the relative numbers of young, middle-aged, and older individuals in a give population.In a population having many members at or nearing reproductive age, significant growth may occur.Age structure may also be represented by a survivorship curve.除环境容纳量外,群体的年龄结构和繁殖方式也影响群体增长率。年龄结构反映中青老的比例关系。若生育年龄的比例大,则显著增长。存活曲线也可以反映年龄结构。
The reproducing members of a population follow a complex adaptive reproductive strategy that has evolved over millennia.Reproductive strategies generally fit into one of two categories: those of r-selected species and those of K-selected species.In r selection individuals reach reproductive age quickly and produce many offspring., Each offspring is small and enters the world with relatively few resources.Out of the many produced, only a few will survive until reproductive age.In K selection, a strategy related to environmental carrying capacity and the need to compete for resource, individuals mature slowly and produce few offspring.However, parents invest a great deal of resources in each offspring;and after a long period of growth to large size, each offspring's chances of survival until reproductive age are high.几千年来,进化形成两个繁殖策略,一是繁殖周期快,后代数量多,每个后代小并可获得资源少。仅有少量存活到生育年龄。一是和环境的容纳量及可匹配资源有关,个体成熟慢并产生很少的后代。但,父母给后代提供很多资源,需要很长的生长期,存活到生育年龄的机遇很高。Limits on Population Size The size of a population is measured in terms of its density.Whether population density is high or low, the distribution of individuals within the population is usually uneven.Common distribution patterns include clumped, uniform, and random.Negative consequences are often attached to high(or rising)population density.These density-dependent factors include increased predation, parasitism, disease, and intraspecific and interspecific competition.Population size may also be reduced by densityindependent factors, a category that includes natural catastrophes.群体的规模也可以用密度来衡量。不论群体密度高与低,群体中个体的分布是不均一的。通用分布模式包括群体的,均匀的,随机的。密度依赖因子包括增加了的捕食,寄生,疾病,种内竞争和种间竞争。群体规模也可因为密度无关因子而降低,包括自然灾难。
The interactions of predators and their prey affect population size in complex ways.Such populations sometimes cycle regularly between growth and decline, in part from the effects of reproductive time lags.In general, predation may slow or stop the growth of a prey population only when many reproducing individuals are eliminated.If only weak, sick, or very young prey are taken, the effect of predation on the density of the population as a whole may be slight.捕食和被捕食的相互复杂关系影响着群体的规模。例如群体规模规律的增长和下降,部分是由于繁殖滞后期的影响。总的来说,当被捕食的是能繁殖的个体时,可能减慢或停止群体的增长。反之,影响就很微弱。An area of controversy among ecologists is the question of whether species diversity in a community tends to generate stability of whether stability encourages species diversity.One aspect of this argument is the hypothesis that a complex food web is more stable than a simple one.In nature, however, many stable, highly diverse communities are characterized by the presence of numerous simple food webs.It may be that stable environments beget diversity because they allow rare species to persist.生物学家一直在争论,是否是物种差异产生稳定性还是稳定性促成了物种差异。一种假设认为,复杂的食物链要比简单的食物链更稳定。实际上,许多稳定的,高差异的社会群体是由众多简单食物链支撑的。可能是稳定的环境引起差异,它只允许很少的物种存留。How Populations Are Distributed
Just as competition, predation, and other elements interact to determine the size of a population within a community, population distribution is the result of many interrelated factors.Overall, the distribution of a population in its potential range depends on locations of food and suitable habitat, interspecific competition for resources, and other variables.Among plants, one of the most effective forms of interspecific competition for resources is allelopathy.Among species that share similar or identical habitat niches, resource partitioning is often seen.In character displacement, closely related species have evolved physical differences in body structures used for exploiting a limited resource.Eventually, such solutions to the need for dividing up a scarce resource may lead to speciation.正如竞争,捕食,和其他因素相互作用影响着群体大小,群体分布是许多相关因子相互作用的结果。总之,潜在的群体分布取决于食物的位置和稳定的住所,种间对资源的竞争,以及其他可变因素。对于大多数植物,种间最有效的资源竞争是异种相生相克关系。许多物种分享相似或相同的生存环境,而进行资源划分。对于特征替换,关系更近的物种已经在进化过程产生了很大体证差异。最终,这种对珍贵资源的划分方式可能导致物种形成。
Human Population: A Case Study in Exponential Growth
The awesome rate of increase that is now a feature of the human population started about 10,000 years ago during the agricultural revolution.At that time, world human population is estimated to have totaled 133 million people;today it has reached a staggering 5 billion.Viewed on a graph, this increase closely resembles the classical exponential growth curve-a growth pattern that cannot be sustained.自从1万年前农业革命以来,人类人口以惊人的速度增长着。当时,世界人口估计在133百万;今天已经达到50亿。几乎接近典型的指数增长曲线,一个不稳定的增长模式。
While the birth rate in many developed countries has slowed, it remains high in less well developed areas of the world.Demographers predict that, if this rate continues, the human population level will reach 30 billion before the end of the twenty-first century.Yet most biologists believe that the earth's carrying capacity for humans is only 10 billion.Clearly, we humans face a serious problem in managing the earth's precious resources while sustaining such a high population density.尽管许多发达国家的出生率降低,但也有高出生率的。人口统计学预测,若出生率持续增加,21世纪末世界人口将达到300亿。然而,生物学家普遍认为,地球的容纳量仅为100亿。显然,人类将面临严重的考验,如何利用如此珍贵的资源维持如此高的人口密度。Glossary
natality出生率
The number of individuals entering the population by reproduction per thousand individuals in the population.mortality 死亡率
The number of individuals leaving the population by death per thousand individuals in the population.exponential growth curve指数生长曲线 Pattern of population growth in which greater and greater numbers of individuals are produced during the successive doubling times;the pattern that emerges when the per capita birth rate remains even slightly above the per capita death rate, putting aside the effects of immigration and emigration.carrying capacity 容纳量,携带量,负载力
The maximum number of individuals in a population(or species)that can be sustained indefinitely by a given environment.logistic growth curve 逻辑生长曲线
Pattern of population growth in which a low density population slowly in creases in size, goes through a rapid growth phase, then levels off once the carrying capacity is reached.age structure 年龄结构
Of a population, the number of individuals in each of several or many age categories.population density 种群密度,群体密度
The number of individuals of a population that are living in a specified area or volume.density-dependent factors密度依赖因子,密度制约因子
population-limiting factors that become more effective as the size of the population increases.intraspecific competition种内竞争
Interaction among individuals of the same species that are competing for the same resources.interspecific competition种间竞争
Two-species interaction in which both species can harmed due to overlapping niches.density-independent factors密度无关因子,非密度制约因子
Population-controlling factors that are not related to the size of the population increases.allelopathy种间感应现象,异种相克相成
A chemical interaction between organisms in which one organism suppresses the germination, growth, or reproduction of the other by releasing toxins into the environment.It occurs particularly between freshwater animals, flowering plants, bacteria, and fungi.survivorship curve 存活曲线,生存曲线
A plot of the age-specific survival of a group of individuals in a given environment, from the time of their birth until the last one dies character displacement特征替换
An alteration of the traits of a species as a result of competition or other interactions with associated species.课后作业:第一篇阅读材料
图书描述
出版日期: 2005年3月1日
《生物专业英语》在第1版的基础上更新了部分较为陈旧的阅读材料,增加了文献数据库检索网上资源检索等资料,内容涉及面广,取材新颖,图文并茂,难易适度,充分反映了现代生物学的发展趋势。在选择补充材料时,着重挑选《生物学文摘》(BA)、《化学文摘》(CA)、《科学引文索引》(SCI)检索和利用的资料,以期通过这些内容提高学生专业学术期刊阅读能力、科技写作能力和文献检索水平。内容涉及动物学、植物学、细胞生物学、遗传学、微生物学、生态学、分子生物学、生物进化、生物信息学、情报学等。书后附有练习答案、专业词汇和参考文献。
________________________________________ 基本信息
出版社: 高等教育出版社;第2版(2005年3月1日)
平装: 302页
开本: 16开
ISBN: 7040161435
条形码: 9787040161434
商品尺寸: 25.6 x 18.2 x 1.4 cm
商品重量: 422 g
ASIN: B0011AUSE6
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《生物专业英语》可作为高校生物类专业英语教材,也可作为从事生物学、农林等研究领域的科学工作者及参加TOEFL或CRE考试学生的考前阅读材料。目录
Lesson One Inside the Living Cell: Structure andFunction of Internal Cell Parts 1 Glossary 3 Exercises 5 Additional Information 8 1.Names of Chemical Element Symbols Commonly Used 8 2.Mathematical Symbols Commonly Used 8 3.Symbols of Length, Capacity and Weight Commonly Used 9 Reading Comprehension 9 Reading Materials 11 The Construction Of Cells 11 Lesson Two Photosynthesis 15 Glossary 17 Exercises 18 Additional Information 21 How to Write a Report or Paper(I)21 Reading Comprehension 26 Reading Materials 27 How Cells Make ATP 27 Using the Electrons Generated by the Citric Acid Cycle to Make ATP 28 Lesson Three Cellular Reproduction:Mitosis and Meiosis 29 Glossary 31 Exercises 32 Additional Information 35 How to Write a Report or Paper(II)35 Reading Comprehension 41 Reading Materials 42 What is Biology 42 The Value of Biology 43 Biological Problems 43 Lesson Four Foundations of Genetics 45 Glossary 46 Exercises 47 Additional Information 51 Chemical Abstract Service 51 Printed Chemical Abstracts(CA)51 Biochemistry Sections of CA(I)52 Reading Comprehension 55 Reading Materials 56 Genes and Characteristics 56 Environmental Influence on Gene Expression 58 Lesson Five Discovering the Chemical Nature of the Gene 59 Glossary 60 Exercises 62 Additional Information 65 Biochemistry Sections of CA(II)65 Reading Comprehension 68 Reading Materials 69 How is the Information in DNA Reproduced so Accurately? 69 What is the Unit of Hereditary Information? 71 Lesson Six The Origin and Diversity of Life 75 Glossary 77 Exercises 78 Additional Information 81 Abbreviations Used in Journals of Biological Sciences 81 Reading Comprehension 83 Reading Materials 84 Earth as a Stage for Life 84 The Unseen Drama: from Molecules to Cells 86 Lesson Seven Fungi:The Great Decomposers 89 Glossary 91 Exercises 92 Additional Information 95 CAS Standard Abbreviations and Acronyms 95 Nature Guide to Authors(I)98 Reading Comprehension 104 Reading Materials 106 The History and Scope of Microbiology 106 Lesson Eight Animal Development 117 Glossary 119 Exercises 121 Additional Information 124 Nature Guide to Authors(Ⅱ)124 Reading Comprehension 130 Reading Materials 131 Animals 131 Lesson Nine The Origin of species 137 Glossary 139 Exercises 140 Additional Information 143 Nature Guide to Authors(Ⅲ)1 43 A.Nature"s Other Submitted Material 1 43 Reading Comprehension 149 Reading Materials 150 How Species Form 150 Lesson Ten The Ecology of Populations 155 Glossary 157 Exercises 158 Additional Information 161 Nature Guide to Authors(IV)161 B.Presubmission Enquiries 161 C.Nature Online Submissions 162 D.Nature Online Revisions 163 E.Getting Published in Nature 165 Reading Comprehension 170 Reading Materials 172 Behavioral Ecology 172 Lesson Eleven Abstracts in Biological Abstracts 1 79 Additional Information 180 Biological Abstracts 180 How to Use Biological Abstracts 184 HOW to Use the Indexes 185 Abbreviations Often Appeared in Biological Abstracts 189 Lesson Twelve The ISI Web of KnowledgeSM Platform:Current and Future Directions 193 Additional Information 203 Web of Science?(I)203 Lesson Thirteen The Handing of Plant Chromosomes 213 Additional Information 223 Web of Science?(Ⅱ)223 Lesson Fourteen Plant Bioinformatics: from Genome to Phenome 241 Additional Information 247 Web of Science?(III)247 Lesson Fifteen Plant Tissue Culture Techniques 257 Additional Information 272 Web of Science?(IV)272 The ISI? Database:The Journal Selection Process 284 Answers to Exercises 289 Glossary of Biological Terms 297 References 301
第二篇:生物教学案10-5
第10章 人体内的物质运输和能量供给
第五节 人体能量的供给
【学习目标】
1、说出人体内能量的供给的过程。
2、说出体温的概念及体温变化对人体的影响。
【知识要点】
一、人体能量的供给
1、转变成人体的组成物质
人体从食物中获得的能量
(利用氧气将营养物质氧化分解释放能量)
热价:蛋白质17.15kJ/g,糖类17.15kJ/g,脂肪38.91kJ/g。
能量等于重量乘以热价。
二、体温
1、体温是指人体内部的温度。
2、测量体温的三个部位:腋窝(36.8℃)、口腔(37.2℃)、直肠(37.5℃)。直肠的温度最接近真实体温。
3、维持体温的相对稳定,是人体进行正常生命活动的基础。
4、“发热”在一定范围内是有利的,当体温达到43℃ 就有生命危险。
【典型例题】
例
1、下列与人体能源物质供给无直接关系的系统是(D)
A、消化系统B、循环系统C、呼吸系统D、内分泌系统
例
2、相同质量的下列营养物质中,含有能量最多的是(C)
A、蛋白质B、糖类C、脂肪D、维生素
例
3、测得某男同学口腔、腋窝和直肠三处的体温分别是37℃、36.5℃、37.2℃,则最接近他实际体温的是(C)
A、36.5℃B、37℃C、37.2℃D、37.5℃
【巩固练习】《补充习题》P45-46。
【学有所得】通过本节课的学习,你有哪些收获?请写下来1、2、3、
第三篇:感 悟 教 师 人 生
感 悟 教 师 人 生
——也谈教师师德
百年大计教育为本,教育大计教师为本,教师大计则师德为本,要培养适合时代需要的高素质人才,教师是否具有良好的道德修养至关重要。
师德,是一个古老而永恒的话题。而提到师德,人们也常会用“灵魂工程师”、“无私奉献”、“蜡烛精神”、“为人师表”做为社会衡量教师的潜标尺。知识经济时代对师德赋予了新的内涵。2006年2月20日《中国教育报》刊载了郭元祥教授撰写的《感悟“教师人生”》一文,作者谈到了“教师之服饰”,认为“细节决定品质,服饰影响人的品位”、“教师服饰无小事”;谈到了“教师之语言”,认为教师“优美的语言是给学生的最美的教育享受”、“教师的语言是实现伟大的教育功能的基本途径”;谈到了“教师之习惯”,认为“好习惯提升人的品质和生活品位,坏习惯糟蹋人的形象和生活层次”、“教育改革核心价值的追求,需要的是创新,而不是习惯”;谈到了“教师之微笑”,认为“教师微笑着面对学生,能给学生一种宽松的师生交往人际环境,使学生感受到教师的理解、关心、宽容和激励”、“教师微笑着面对同事,校长微笑着面对教师,有利于构建合作性的同事关系,有利于营造一种积极向上、追求卓越、团队学习的发展型组织”;作者还谈到了“教师之思想”,认为“思想有多远,我们就能走多远”、“一个有思想的教师一定是学生喜爱的教师,一个有魅力的教师,一个有精神感召力的教师”;最后,作者谈到了“教师之信念”,认为教师的核心竞争力,“也许就是教师的信念”、“教师的信
念蕴含着教师的信誓,教师的激情”、“教师的信念中还包含着责任与使命、爱心与真情、坚持不懈与持之以恒”。因此我认为“教师人生”这个新的论断是一种对师德的新的诠释。
所谓教师人生,就是不仅仅把教育作为一个职业来看待,而是将教育当成自己人生的一个部分来对待,来体验,来充实,来完成。而这样以对待自己的生命的态度对待教育,向爱惜自己的生命一样珍惜教育事业的境界,我认为正是一种高尚的师德体现。那么,如何使教师人生精彩而有价值呢?
一、“教师人生需要生命的活力,需要生命的激情,需要生命的灵动”
车尔尼雪夫斯基曾说过这样一段名言:一个没有受到献身的热情所鼓舞的人,永远不会做出什么伟大的事情来。作为教师,我们不仅需要一颗对学生的爱心,相信“皮格马利翁效应”,给每个学生以“象牙姑娘”的期待。我们还需要善于结合学生的爱好和兴趣情况,在引导和启发下开展教育教学。要有一颗耐心,耐心的等待学生的进步,等待学生从兴趣茫然到对所学课程热爱的过程。同时更要求教师要不断从生活的感悟中提升自己的人生境界,完善自己的道德情操。
精深的生活感悟可以提升教师的人生境界和道德情操。作为一名教师要能在外界丰富多彩的环境中给自己留下一个空间,静下心来以自己的方式来让自己的生命充实。焕发教师人生生命的活力,生命的激情和生命的灵动。比如,有的教师就曾这样感悟到:读书依然是她最主要的休闲方式。她读了一些专业书籍,努力勾勒为师者的形象;投身教育科
研,做研究性、有灵气的教师;重朔师生关系,做民主型、有魅力的教师;形成自身风格,做个性化、有才情的教师。她还读了不少闲书,在文化的浸染中滋养心灵,努力在血液中注入人文关怀,让生活中充满情趣和生机。她坚持读书,因为她觉得做为一名当前社会环境下的职业学校的教师,决不只是机械的备课、上课、批改作业更应该结合当前社会的发展,为专业发展的新需要而广闻博取,咀嚼经典,接受时尚。
人们总是喜欢把教师看作是“人类灵魂的工程师”,把教育事业比作是“太阳底下最光辉的职业”,无形中确定了教师的工作性质就是要塑造人的灵魂,又把教师的这种工作推到了崇高与伟大的位置上。而这些都应该成为历史性的认识。因为教育本身就是一项成长中的事业,这种成长,不仅有学生的,也有教师的。教育,不是知识的蔓延、思想的传递,更不是按一定的模式去生产一种产品。教育,应该是一种成长影响另一种成长。
二、“教师人生需要感动。感动自己,感动学生,感动家长,感动社会……”
感动是一种情感操练,是一种有益的陶冶,更是继续教师人生的一份支持。作为一名职业学校的教师,面对着学生从做人品德的提升到能主动去领悟专业知识再到学生的成功就业和就业岗位上的出色表现。我们要不断的在学生的改变中感动自己。进而把这种感动化作一份继续教师人生的动力和行动,因为行动是感动的延伸,是我们尽好责任、做好教师的关键。在职业学校的教育教学中,很关键的一个过程是唤起学生的学习兴趣和培养学生学习的坚持力。我们要善于发现学生的兴趣点,然后巧妙的切入。比如,学生的某项专业
特长的粗浅爱好,青春期学生的好奇好胜,一次偶然的积极表现等等,都可以让我们当作一个教育契机,把学生表现出来的一点点积极的倾向演变、扩大成真正的兴趣进而稳定成爱好和继续发展的方向。所以一些丰富的专业实践活动,比如,一次外出的表演机会,一个被选为礼仪代表的小事等都可以让我们来变成让学生感动学生自己的机会。而学生的进步更需要家长的支持和肯定。所以,我们在感动了学生的同时也要创造机会让家长来重新认识自己的子女。比如把专业演出带到学生家乡而带给家长的那份感动,可以让我们把在校的一份工作效果扩大到无限。而每一个职业学校的学生的顺利工作和工作岗位的突出成绩,也很好的达成了职业教育的社会责任。
三、“教师人生需要责任,需要体验教育的快乐,感受教育的幸福。”
教师人生需要责任,要有以一种对人生负责的态度,对学生负责、对家长负责、对职业负责、对社会负责。使教师人生成为一种信念。可以这样说,一个教师具有什么样的思想,也就注定了他有什么样的教育人生。现在,对于很多老师来说,都很难摆脱生存的压力和物质利益的诱惑,因而很少关注自己的内心世界,致使很多人思想逐渐萎靡,灵魂日益空虚,在教育路上只剩下忙忙碌碌的空壳。再加之教育理想与教育现实之间残酷的冲突,也让更多的老师失去了教育的热情,产生了教育懈怠的思想、出现了教育倦怠的现象。这样的教育氛围,又怎能影响学生具有积极进取的人生态度呢?所以作为我们教师自己,应该主动地去摆脱这种不良情绪的影响,建立自己乐观向上的人生态度和积极进取的教育思想。而要摆脱眼前的困境,走出心灵的低谷,就要像郭元
详先生所说,赶快去读书。因为只有读书,才能充实我们空洞的大脑,丰盈我们单薄的灵魂,还我们健康的人格。我们在读书中才能找回从前的梦想,完成真正的自己,用积极的思想谱写出自己瑰丽的教育人生。杨启亮教授在一次学术报告会上说,教师的职业境界有四个层次,一是把教育看成是社会对教师角色的规范、要求;二是把教育看作出于职业责任的活动;三是把教育看作是出于职业良心的活动;四是把教育活动当作幸福体验。教育从根本意义上来说,就是以人为本,关注人的幸福,培养人的生活能力,培养人的幸福能力。教师的最高境界是把教育当作幸福的活动。幸福的教育需要幸福的教师:有了幸福的教师,才可能有幸福的学习,才可能有幸福的学生。当枯燥的概念、专业的表达方式被我们的教师用生命的激情去表达和诠释的时候,教育显得如此的独特、美丽。我们在这样的经历中关注着自己教学生命的成长发展,感受着教育理想的生命活力。那滋味,是快乐,是满足,是成就!
师德建设是当前教育工作的热点,而且也引起了全社会的广泛关注。而师德的标准不是唯一的,每一名教师无论是将教育当作一份事业或是将教育当成人生,通过师德建设问题的探讨,我们每位教师都能认真的审视自己的教育经历和行为,对整个教师队伍的师德状况,对本人的师德情况引发思考,提高教师师德的境界。同时在教师人事制度改革的今天,我们职业学校更需要一种与学校共甘苦、同发展的“校园精神”!所以在抓师德建设中,进行“爱校”教育也应该是一个重要环节。
最后引用我最欣赏的一句教育名言,作为教师人生的最高境界。和同事们共勉:
教育是事业,事业的成功在于奉献; 教育是科学,科学的探索在于求真; 教育是艺术,艺术的生命在于创新”
第四篇:高三生物教学案:基因工程
杨卫东生物工作室www.aqyz.net/bb
高三生物教学案:基因工程
班级 姓名
一、基础填空:
1、基因工程概念
基因工程又叫 或。它是按照人们的意愿,把一种生物的个别基因复制出来,加以修饰改造,然后放到 的细胞里,生物的遗传性状。
2、基因的操作工具
(1)基因的剪刀—— 一种限制酶只能识别 特定的核苷酸序列,并在特定的位点切割DNA分子。
(2)基因的针线—— 把两条DNA末端之间的缝隙“缝合”起来。
(3)基因的运输工具—— 运载体能够在宿生细胞中复制并稳定保存,具有多个限制酶切点,具有标记基因。常见的运载体有、、等。
3、基因操作的基本步骤
(1)提取目的基因 有两条途径: 和。
(2)目的基因与运载体结合 用 酶处理目的基因和运载体,而后加入DNA连接酶,使目的基因载入到运载体中,形成。(3)将目的基因导入受体细胞 重组DNA导入受体细胞。
(4)目的基因的检测与表达 根据 判断目的基因导入与否;根据受体细胞表现出特定的 判断目的基因的表达与否。
二、单选题:
1.下列不属于获取目的基因的方法是 A.“鸟枪法” B.转录法 C.反转录法 D.根据已知氨基酸序列合成法 2.下列哪项不是基因工程中经常使用的用来运载目的基因的载体
A.细菌质粒
B.噬菌体 C.动植物病毒
D.细菌核区的DNA 3.(2005·全国卷Ⅰ·3)镰刀型细胞贫血症的病因是血红蛋白基因的碱基序列发生了改变。检测这种碱基序列改变必须使用的酶是()A、解旋酶 B、DNA连接酶 C、限制性内切酶 D、RNA聚合酶 4.(2005·全国卷Ⅲ·5)科学家通过基因工程的方法,能使马铃薯块茎含有人奶主要蛋白。以下有关基因工程的叙述,错误的是()A、采用反转录的方法得到的目的基因有内含子
B、基因非编码区对于目的基因在块茎中的表壳是不可缺少的 C、马铃薯的叶肉细胞可用为受体细胞
D、用同一种限制酶,分别处理质粒和含目的基因的DNA,可产生粘性末端而形成重组DNA分子 5.有关基因工程的叙述正确的是
A.限制酶只在获得目的基因时才用 B.重组质粒的形成是在细胞内完成的
C.质粒都可作为运载体 D.蛋白质的结构可为合成目的基因提供资料
6、下列有关基因工程操作的正确顺序是()①目的基因的检测和表达 ②目的基因与运载体结合 ③将目的基因导入受体细胞 ④提取目的基因 A.①②③④ B.④③②① C.④②③① D.③④②①
7.不属于质粒被选为基因运载体的理由是()
A.能复制
B.有多个限制酶切点
C.具有标记基因 D.它是环状DNA 8.有关基因工程的叙述中,错误的是()杨卫东生物工作室www.aqyz.net/bb A. DNA连接酶将黏性未端的碱基对连接起来 B. 限制性内切酶用于目的基因的获得 C. 目的基因须由运载体导入受体细胞 D. 人工合成目的基因不用限制性内切酶
9、细菌常常作为基因工程的受体细胞,下列理由较充分的是
()
A.形体微小 B.结构简单 C.容易监测 D.繁殖速度快
10、基因工程的“四步曲”中未发生碱基互补配对的是()A.用鸟枪法分离出抗病毒基因
B.将人的胰岛素基因与大肠杆菌质粒结合,形成重组质粒 C.将重组质粒导入受体细胞 D.抗病毒基因的表达
11、基因工程又叫DNA重组技术,是在分子水平上对生物的定向改造。以下的叙述中,正 确的是
A.一种限制酶只能识别一种特定的核苷酸序列 B.基因工程所用的工具酶是限制酶、连接酶和运载体 C.限制酶的切口一定是GAATTC碱基序列 D.目的基因就是指重组DNA质粒
()
三、多选题
12.目前常被使用的基因载体有()A.质粒
B.噬菌体
C.染色体
D.动、植物病毒
13.人们利用基因工程的方法,用大肠杆菌生产人类胰岛素,这一过程涉及到()A.用适当的酶对胰岛素基因与运载体进行切割并连接 B.把重组后的DNA分子导入受体细菌内进行扩增 C.检测重组DNA分子是否导入受体细菌内并表达出性状 D.筛选出能产生胰岛素的“工程菌”
14.科学家已能运用基因工程技术,让羊合成并分泌抗体。相关叙述不正确的是()A.该技术将导致定向的变异 B.受精卵是理想的受体细胞
C.垂体分泌的催乳素能促进效应B细胞产生抗体 D.采用鸟枪法法获得目的基因
15、下列关于基因工程的说法正确的是()A.基因工程的设计和施工都是在分子水平上进行的
B.目前基因工程中所有的目的基因都是从供体细胞直接分离得到的 C.基因工程能使科学家打破物种界限,定向地改造生物性状
D.只要检测出受体细胞中含有目的基因,那么目的基因一定能成功地进行表达
四、非选择题
16.(2005·江苏生物·38)在植物基因工程中,用土壤农杆菌中的Ti质粒作为运载体.把目的基因重组人Ti质粒上的T-DNA片段中,再将重组的T-DNA插入植物细胞的染色体DNA中。
(1)科学家在进行上述基因操作时,要用同一种 分别切割质粒和目的基因,质粒的黏性末端与目的基因DNA片段的黏性末端就可通过 而黏合。
(2)将携带抗除草剂基因的重组Ti质粒导入二倍体油菜细胞,经培养、筛选获得一株有抗除草剂特性的转基因植株。经分析,该植株含有一个携带目的基因的T-DNA片段,因此可以把它看作是杂合子。理论 杨卫东生物工作室www.aqyz.net/bb 上,在该转基因植株自交F1代中,仍具有抗除草剂特性的植株占总数的,原因是。
(3)种植上述转基因油菜,它所携带的目的基因可以通过花粉传递给近缘物种,造成“基因污染”。如果把目的基因导人叶绿体DNA中,就可以避免“基因污染”,原因是。
17、在药品生产中,有些药品如干扰素,白细胞介素,凝血因子等,以前主要是从生物体的组织、细胞或血液中提取的,由于受原料来源限制,价价十分昂贵,而且产量低,临床供应明显不足。自70年代遗传工程发展起来以后,人们逐步地在人体内发现了相应的目的基因,使之与质粒形成重组DNA,并以重组DNA引入大肠杆菌,最后利用这些工程菌,可以高效率地生产出上述各种高质量低成本的药品,请分析回答:
(1)在基因工程中,质粒是一种最常用的,它广泛地存在于细菌细胞中,是一种很小的环状 分子。
(2)在用目的基因与质粒形成重组DNA过程中,一般要用到的工具酶 是 和。
(3)将含有“某激素基因”的质粒导入细菌细胞后,能在细菌细胞内直接合成“某激素”,则该激素在细菌体内的合成包括 和 两个阶段。
(4)在将质粒导入细菌时,一般要用 处理细菌,以增大。
18、中国青年科学家陈炬成功地把人的抗病毒干扰素基因“嫁接”到烟草的DNA分子上,使烟草获得了抗病毒能力,试分析:
(1)陈炬的“嫁接”技术称为___________。
(2)人的基因能接到植物体内,其物质基础是__________________________。
(3)烟草有了抗病毒能力,这表明烟草体内“嫁接”的基因经___________产生了___________。这个事实说明:人和植物共用一套___________,且蛋白质的合成方式__________________。
19.干扰素是治疗癌症的重要药物,它必须从血中提取,每升人血只能提取0.05 μg,所以价格昂贵。现在美国加利福尼亚的基因公司用如下图的方式生产干扰素,试分析其原理和优点。
(1)从人的淋巴细胞中取出___________,使它同细菌质粒相结合,然后移植到酵母菌的细胞里,让酵母菌__________________。
(2)酵母菌能用___________繁殖,速度很快,能大量生产___________,不但提高了产量,也降低了成本。
(3)酵母菌能产生干扰素,这个事实说明,人和酵母菌共用一套___________。
19、豇豆对多种害虫具有抗虫能力,根本原因是豇豆体内具有胰蛋白酶抑制剂基因(CpTI基因)。科学家将其转移到水稻体内后,却发现效果不理想,主要原因是CpTI蛋白质的积累量不足。经过在体外对CpTI基因进行了修饰后,CpTI蛋白质在水稻中的积累量就得到了提高。修饰和表达过程如下图所示:
杨卫东生物工作室www.aqyz.net/bb
请根据以上材料,回答下列问题:
⑴CpTI基因是基因工程中的 基因,“信号肽”序列及“内质网滞留信号”序列的基本组成单位是
,在①过程中,首先要用
酶切开,暴露出
,再用
酶连接。
⑵在转基因过程中,供体细胞是
,受体细胞是
。⑶②过程称为。
⑷检测修饰后的CpTI基因是否表达的最好方法是。
基因工程答案
(一)基因工程的基本内容
1、基因工程概念
基因工程又叫基因拼接技术或DNA重组技术。它是按照人们的意愿,把一种生物的个别基因复制出来,加以修饰改造,然后放到另一种生物的细胞里,定向地改造生物的遗传性状。
2、基因的操作工具
(1)基因的剪刀——限制性内切酶 一种限制酶只能识别一种特定的核苷酸序列,并在特定的位点切割DNA分子。
(2)基因的针线——DNA连接酶 把两条DNA末端之间的缝隙“缝合”起来。
(3)基因的运输工具——运载体 运载体能够在宿生细胞中复制并稳定保存,具有多个限制酶切点,具有标记基因。常见的运载体有质粒,噬菌体、动植物病毒等。
3、基因操作的基本步骤
(1)提取目的基因 有两条途径:直接分离基因和人工合成基因。
(2)目的基因与运载体结合 用同一限制酶处理目的基因和运载体,而后加入DNA连接酶,使目的基因载入到运载体中,形成重组DNA。
(3)将目的基因导入受体细胞 重组DNA导入受体细胞。
(4)目的基因的检测与表达 根据标记基因判断目的基因导入与否;根据受体细胞表现出特定的性状判断目的基因的表达与否。
二、单选题:BDAAD CDADC A
三、多选题 12ABD 13ABCD 14CD 15AC
四、非选择题
16.(1)限制性内切酶,碱基互补配对。
(2)3/4,雌雄配子各有1/2含抗除草剂基因;受精时,雌雄配于随机结合。
(3)原因是 叶绿体遗传表现为母系遗传,目的基因不会通过花粉传递丽在下一代中显现出来。
17、(1)基因的运载体 DNA 杨卫东生物工作室www.aqyz.net/bb(2)限制性内切酶 DNA连接酶(3)转录 翻译
(4)氯化钙 细菌细胞壁的通透性
18、(1)基因工程(2)人和植物的遗传物质DNA结构基本相同(3)转录和翻译 抗干扰素 遗传密码 基本相同
19、(1)干扰素基因 合成干扰素(2)出芽生殖 干扰素(3)遗传密码
20、⑴目的四种脱氧核苷酸
限制性内切酶
黏性末端
DNA连接
⑵豇豆
水稻
⑶转录 ⑷让多种害虫食用水稻叶片
第五篇:高三生物教学案封面
高三生物试题集
班级:_______________ 姓名:_______________ 把简单的事情做到极致便是奇迹
浅谈高三生物复习方法与技巧
生物学科属于自然科学,也是基础教育必修的一门学科。然而由于受中考与高考指挥棒的影响,一些学校为了片面追求升学率,生物学科的教学在中学往往没有得到足够的重视。因为初中生物不属于中考科目,许多初中学校的生物课基本属于走过场,往往是在会考前划出一定的范围或指定几套练习让学生死记硬背。进入高中,由于高中生物无论从知识的深度还是广度上,都与初中生物有很大的不同,所以相当一部分同学学习生物比较困难。笔者从事高三毕业班的生物教学多年,亲眼所见一些学生学习生物的被动与苦恼。其实,高三生物复习并不是杂乱无章的,以下是老师们的一些体会,其中提到的方法和技巧可供同学们借鉴。
一、几种错误认识和做法
1.很多人说生物是理科中的文科,学生物背背书就行。学生物,的确要背书,但如果要真正学好生物,单靠死记硬背是绝不可能的。
2.有些学生不重视基础知识,上课不喜欢听老师讲课,也不愿看书,更不愿对教材中基本概念、规律加以理解,在平时的课堂上总是一味地忙着做题,希望通过做题来熟悉相应的知识点。这种做法其实是不利于生物成绩全面提高的。
3.部分学生一进入高三的复习,就急于做套题(各地模拟题),其实这也是不好的。因为此时学生对知识的掌握不系统不完整,还不具备做高考模拟题的能力。各地模拟题往往是按高考的标准来命制的,它对学生的能力要求比较高,而我们学生各方面综合能力的形成还有一个过程。所以,在第一轮复习过程中,最好是跟着老师的进度,做相应的考点训练。
4.相当一部分学生没有养成做题的良好习惯,喜欢把参考答案放在一边,只要不会,马上就看答案,不愿意更深层次地去思考问题。很多学生题做了一大堆,能力并没有提高,就是这个原因。
二、根据生物学科的特点,掌握科学的学习方法
1.掌握规律。规律是事物本身固有的本质的必然联系。生物有自身的规律,如结构与功能相适应,局部与整体相统一,生物与环境相协调,以及生物从简单到复杂、从低等到高等、从水生到陆生的进化过程等。掌握这些规律将有助于生物知识的理解与运用,如学习线粒体就抓结构与功能相适应:①线粒体外膜,将其与细胞周围分隔开,使有氧呼吸集中在一定区域内进行;②内膜向内折叠形成嵴,扩大了膜面积,有利于与有氧呼吸有关的酶在其上有规律地分布,使各步反应高效有序地进行(有氧呼吸第三阶段);③内膜围成的腔内有基质,基质中也有酶的分布,有酶促反应进行(有氧呼吸第二阶段);④由于有氧呼吸第一阶段不在线粒体中进行,因而线粒体是有氧呼吸的主要场所。..2.突破难点。有些知识比较复杂,或是过于抽象,同学们学起来感到有困难,这时就应化难为易,设法突破难点。通常采用的方法有以下两种:
(1)复杂问题简单化。生物知识中,有许多难点存在于生命活动的复杂过程中,难以全面准确地掌握,而将复杂问题简单化能使知识一目了然。例如人体体温的调节,我们只要抓住健康人产热与散热要达到动态平衡就很容易掌握要点。产热的机制可以有骨骼肌战栗(收缩),代谢加强则依赖甲状腺激素和肾上腺素分泌增加来调节;散热则与皮肤毛细血管和汗腺有关。在分析的过程中,学生很容易体会到体温的调节是一个神经——体液的调节过程。
(2)抽象问题形象化。有些知识,与现实联系少,理解起来困难。这时,要尽量借助某种方式,使之与实际联系起来,便于理解。比如,有丝分裂和减数分裂的学习,一直是一些学生觉得非常抽象的。如果我们能以2对同源染色体为例独立画出各时期的图形,我想关于图像的识别、染色体、染色单体的数量变化和各时期主要特征的有关知识,应该就不在话下了。因此,学习生物常常需借助图形、表格、模型、标本、录像等形象化的手段来帮助理解一些抽象的知识。
3.归纳总结。在生物第一轮的复习过程中,老师一般都是按教材的顺序将知识分块学习。但当学完一部分内容之后,就应该把分散在课本不同章节的分块的知识联系起来,归纳整理成系统的知识。这样不仅可以在脑子里形成完整的知识结构,而且也便于理解和记忆。归纳总结要做到“三抓”:一抓顺序,二抓联系,三抓重点。抓顺序就是要将各知识点按照本身的逻辑关系将其串联。抓联系就是要掌握各知识点之间的内在联系,理清点线的纵横关系,由线到面,扩展成知识网络。抓重点就是抓主流,进行归纳总结,不能大杂烩,胡子眉毛一把抓。
4.图表过关。生物图表题是一种难度大,灵活性强,知识覆盖面广,能力要求较高的综合性试题。特别是非选择题中的图表作答题,许多学生感到十分棘手,这其中除了与基础知识不扎实有关外,更重要的是没有掌握运用好一种科学的思维方法。教材中有大量的图表,这些图表在课后复习时应很好地利用。我们可以尝试着先将课本中所有的图表题过关,再结合参考资料上的图表题专门训练。非选择题生物图表题的一般解法归纳为“审题、定点、作答”3个步骤。审题就是要读懂题目,弄清楚题意。定点就是在审题的基础上,确定题目所涉及到的课本中的知识点。作答是在审题、定点的基础上,做出与题目要求观点一致的答案,前两步是对生物图表题的分析,此步骤则是对分析的结果进行说明,即进行文字表达,它要求科学准确,言简意赅,要引导学生运用相关的专业术语来答题。还要注意文字表达的角度与题干保持一致,密切相关,否则就会出现文不对题的情况。
5.学以致用。生物学是一门与生产和生活联系非常紧密的科学。我们在复习生物学知识时,应该注意理解科学技术和社会(STS)之间的相互关系,理解所学知识的社会价值,并且运用所学的生物学知识去解释一些现象、解决一些问题。近几年的广东高考题越来越接近生产生活实际,许多材料选自平常老百姓的日常生活。在命题材料的选择上,往往以社会热点问题切入,所以热点要引起足够的重视,如生态农业、环境污染、能源问题、全球气候问题(关注哥本哈根会议)等。
三、从小处着手,重视能力培养
1.学会“看”
高考题目千变万化,但 “题在书外,理在书中”。在复习中,要认真阅读课本,对课本的核心知识要达到“滚瓜烂熟”的地步。此外还要注意以下几方面的内容,一是旁文即教材旁边提供的小资料或小问题,这些都是对教材内容的补充。在看书时加以关注,一方面有利于拓展知识面,另一方面有利于把握重点;其次是教材中的插图,有模型,有坐标曲线,也有示意图,这些不仅是高考直接考察的内容,而且也是帮助学生加强理解的辅助工具;然后是课后的阅读资料,这部分一般不做考试要求,但是这些课外阅读资料与正文有一定联系,关注之后有利于帮助学生理解正文,事实上,考试题目的背景有时候也会采用这些材料。
2.学会“听”
听课听什么?要听老师分析本节课的重点、难点、考点和疑点;听自己在预习过程中所未能理解的内容;听老师对相关问题(或习题)是如何分析的。不仅要认真听,还要做好必要的笔记。笔记如何做也有一定的讲究,有些同学喜欢将老师的板书一字不漏地记下来,其实大可不必。我们只要将老师补充的一些重要的知识点、结论做一些笔记,对于习题也只需记一些主要的分析过程,课后再进行必要的完善即可;万万不可顾此失彼,因为忙着做笔记而忽略了听课。
3.学会“说”
课堂上对一些问题的分析和解决,不要总是依靠于老师的讲。有些同学习惯于老师的满堂灌,不喜欢自己整理知识和组织语言,这就很难将知识的理解上升到一定的高度。每一位同学都应该积极思考,我怎么解决这个问题?这种思维方法好吗?哪种表达更为准确?所以在课堂上要敢于大胆表述自己的观点,提高自己的语言表达能力。
4.学会“练”
对于某一部分知识点的掌握情况,光会听和会看还不行,还需要通过一定的习题来巩固。一般建议大家在老师的推荐下选择合适的复习资料,但同学们万万不要陷入“题海”,要掌握好训练的“度”。在训练过程中,建议大家准备一个错题本,将典型的错题整理到错题集上,做错的题目实际上是宝贵的资源,能够提醒你在以后的复习中避免出错。
5.学会“思”
古语云:“学而不思则罔,思而不学则殆”。此言提醒我们在学习的过程中要经常进行反思。其实,学习生物知识最关键的是学会其中的学科思想和答题方法,学会思维。因而,同学们在看书或做题时,要多想为什么?是否还有其他的方法或表述?此类习题有何规律?在反思中提高自己的生物思维模式和答题能力。
6.学会“调”
整个高三的复习都是紧张有序的,整个过程伴随着大大小小的考试,伴随着学校、家庭的期望与个人价值的实现,而最终都要通过考试体现出来。高考是对一个考生知识与技能、方法与心理等各项综合素质全方位的考查,要想力挫群雄,六月折桂,除掌握必备的知识、技能、方法外,心理素质也是高考成败的重要因素之一。要做到在高考时沉着应考,处惊不变,在加强解题训练的同时,应加强心理训练。
总之,高考本身就是一门综合的艺术,需要大家在复习过程中不断领悟。而生物的学习虽无定法,但有章可循。只要我们遵循认知的规律,善于归纳小结,看练结合,用心体会,就一定能找到一套适合自己的学习方法。